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David S. Wishart
Researcher at University of Alberta
Publications - 564
Citations - 93527
David S. Wishart is an academic researcher from University of Alberta. The author has contributed to research in topics: Metabolomics & Medicine. The author has an hindex of 108, co-authored 523 publications receiving 76652 citations. Previous affiliations of David S. Wishart include La Trobe University & International Agency for Research on Cancer.
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Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and potential biomarkers.
Ammar Hassanzadeh Keshteli,Karen Madsen,Rupasri Mandal,Guy E. Boeckxstaens,Premysl Bercik,Giada De Palma,David E. Reed,David S. Wishart,Stephen Vanner,Levinus A. Dieleman +9 more
TL;DR: Evaluation of the metabolomic profile of patients with irritable bowel syndrome offers an opportunity to identify novel pathophysiological targets and biomarkers that could discriminate this disorder from related conditions.
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Magnetic Resonance Diagnostics: A New Technology for High-Throughput Clinical Diagnostics
David S. Wishart,Lori M.M. Querengesser,Brent Allan Lefebvre,Noah Alexander Epstein,Russell Greiner,Jack Barless Newton +5 more
TL;DR: Because MRD is fully automated (sample handling, spectral collection, and spectral analysis are all handled by robots or computers), this technique offers the potential for high-throughput, comprehensive, and inexpensive chemical analysis of a wide range of biofluid samples.
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Metabolite profiling and expression analysis of flavonoid, vitamin C and tocopherol biosynthesis genes in the antioxidant-rich sea buckthorn (Hippophae rhamnoides L.).
Tahira Fatima,Vigya Kesari,Ian Watt,David S. Wishart,J. Todd,William Schroeder,Gopinadhan Paliyath,Priti Krishna,Priti Krishna +8 more
TL;DR: Orthologs of 15 flavonoid biosynthesis pathway genes were identified within the transcriptome of sea buckthorn mature seeds, expanding the genomic resources for this nutritionally important plant.
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Molecular signatures of end-stage heart failure.
David T.S. Lin,Zsuzsanna Hollander,Anna Meredith,Ellamae Stadnick,Ellamae Stadnick,Mayu Sasaki,Gabriela V. Cohen Freue,Pooran Qasimi,Alice Mui,Raymond T. Ng,Robert Balshaw,Janet Wilson-McManus,David S. Wishart,David Hau,Paul Keown,Robert McMaster,Bruce M. McManus +16 more
TL;DR: Multiple "-omic" analyses support the convergence of dramatic changes in molecular processes underlying IHD and NICM at end stage of chronic heart failure.
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Metformin and Dipeptidyl Peptidase-4 Inhibitor Differentially Modulate the Intestinal Microbiota and Plasma Metabolome of Metabolically Dysfunctional Mice.
Paul M. Ryan,Elaine Patterson,I. Carafa,Rupasri Mandal,David S. Wishart,Timothy G. Dinan,John F. Cryan,Kieran Tuohy,Catherine Stanton,R. Paul Ross +9 more
TL;DR: This study represents the first direct comparison of the microbiota-modifying effects of metformin and a DPP-4 inhibitor, and proposes several putative microbial targets both in terms of novel therapeutic development and adverse effect prevention.