D
David S. Wishart
Researcher at University of Alberta
Publications - 564
Citations - 93527
David S. Wishart is an academic researcher from University of Alberta. The author has contributed to research in topics: Metabolomics & Medicine. The author has an hindex of 108, co-authored 523 publications receiving 76652 citations. Previous affiliations of David S. Wishart include La Trobe University & International Agency for Research on Cancer.
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The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data.
David S. Wishart,Brian D. Sykes +1 more
TL;DR: It is shown that by combining both 1H and 13C chemical-shift indices to produce a ‘consensus’ estimate of secondary structure, it is possible to achieve a predictive accuracy in excess of 92%.
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The chemical shift index: A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
TL;DR: This new method for rapidly and quantitatively determining the identity, extent, and location of secondary structural elements in proteins based on the simple inspection of the alpha-CH 1H resonance assignments is found to be almost as accurate as the more traditional NOE-based methods of determining secondary structure.
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Relationship between nuclear magnetic resonance chemical shift and protein secondary structure.
TL;DR: An analysis of the 1H nuclear magnetic resonance chemical shift assignments and secondary structure designations for over 70 proteins has revealed some very strong and unexpected relationships.
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DrugBank 4.0: shedding new light on drug metabolism
Vivian Law,Craig Knox,Yannick Djoumbou,Timothy Jewison,An Chi Guo,Yifeng Liu,Adam Maciejewski,David Arndt,Michael Wilson,Vanessa Neveu,Alexandra Tang,Geraldine Gabriel,Carol Ly,Sakina Adamjee,Zerihun T. Dame,Beomsoo Han,You Zhou,David S. Wishart +17 more
TL;DR: The latest update of DrugBank, DrugBank 4.0, has been further expanded to contain data on drug metabolism, absorption, distribution, metabolism, excretion and toxicity (ADMET) and other kinds of quantitative structure activity relationships (QSAR) information.
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PHAST: A Fast Phage Search Tool
TL;DR: PHAge Search Tool (PHAST) is a web server designed to rapidly and accurately identify, annotate and graphically display prophage sequences within bacterial genomes or plasmids.