David S. Wishart

TL;DR: In this paper, the legal person is not a single concept but a variety of constructs of particular programs of legal change, and the person is a discursive structure within a rationality of government.

TL;DR: This year's Pacific Symposium in Biocomputing solicited papers that focused specifically on describing novel methods for the acquisition, management and analysis of metabolomic data, particularly interested in papers that covered one of the five following topics: metabolomics databases; 2) metabolomics LIMS; 3) spectral analysis tools for metabolomics; 4) medical or applied metabolomics.

TL;DR: In this article, the authors developed an in-silico model to predict the permeability of compounds based on the parallel artificial membrane permeability assay (PAMPA), a non-cellular lab-based assay, and used the 3D-RISM theory with the Kovalenko-Hirata (KH) closure to calculate the excess chemical potentials of a large set of compounds.

TL;DR: A protein-based biosensor that can sensitively detect negatively charged ENPs in aquatic matrices is generated using a genetically engineered green fluorescent protein with a poly-lysine tag to facilitate its electrostatic interaction with commercially available negatively charged NPs.

TL;DR: In this article, the authors identify metabolomic markers in maternal first-trimester serum for the detection of fetal congenital heart defects (CHDs) using mass spectrometry (direct injection/liquid chromatography and tandem mass spectra) and nuclear magnetic resonance spectrometric-based metabolomic analyses on maternal serum.