H
Hardev Pandha
Researcher at University of Surrey
Publications - 376
Citations - 13796
Hardev Pandha is an academic researcher from University of Surrey. The author has contributed to research in topics: Oncolytic virus & Cancer. The author has an hindex of 57, co-authored 349 publications receiving 11617 citations. Previous affiliations of Hardev Pandha include Oncolytics Biotech, Inc. & St George's, University of London.
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Journal ArticleDOI
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Fredrick R. Schumacher,Ali Amin Al Olama,Sonja I. Berndt,Sara Benlloch,Mahbubl Ahmed,Edward J. Saunders,Tokhir Dadaev,Daniel Leongamornlert,Ezequiel Anokian,Clara Cieza-Borrella,Chee Goh,Mark N. Brook,Xin Sheng,Laura Fachal,Joe Dennis,Jonathan Tyrer,Kenneth Muir,Kenneth Muir,Artitaya Lophatananon,Artitaya Lophatananon,Victoria L. Stevens,Susan M. Gapstur,Brian D. Carter,Catherine M. Tangen,Phyllis J. Goodman,Ian M. Thompson,Jyotsna Batra,Jyotsna Batra,Suzanne K. Chambers,Suzanne K. Chambers,Leire Moya,Leire Moya,Judith A. Clements,Judith A. Clements,Lisa G. Horvath,Wayne D. Tilley,Gail P. Risbridger,Gail P. Risbridger,Henrik Grönberg,Markus Aly,Tobias Nordström,Paul D.P. Pharoah,Nora Pashayan,Johanna Schleutker,Teuvo L.J. Tammela,Csilla Sipeky,Anssi Auvinen,Demetrius Albanes,Stephanie J. Weinstein,Alicja Wolk,Alicja Wolk,Niclas Håkansson,Catharine M L West,Alison M. Dunning,Neil G. Burnet,Lorelei A. Mucci,Edward Giovannucci,Gerald L. Andriole,Olivier Cussenot,Geraldine Cancel-Tassin,Stella Koutros,Laura E. Beane Freeman,Karina Dalsgaard Sørensen,Torben F. Ørntoft,Michael Borre,Lovise Maehle,Eli Marie Grindedal,David E. Neal,David E. Neal,David E. Neal,Jenny L Donovan,Freddie C. Hamdy,Richard M. Martin,Ruth C. Travis,Timothy J. Key,Robert J. Hamilton,Neil E. Fleshner,Antonio Finelli,Sue A. Ingles,Mariana C. Stern,Barry S. Rosenstein,Sarah L. Kerns,Harry Ostrer,Yong-Jie Lu,Hongwei Zhang,Ninghan Feng,Xueying Mao,Xin Guo,Guomin Wang,Zan Sun,Graham G. Giles,Melissa C. Southey,Robert J. MacInnis,Robert J. MacInnis,Liesel M. FitzGerald,Liesel M. FitzGerald,Adam S. Kibel,Bettina F. Drake,Ana Vega,Antonio Gómez-Caamaño,Robert Szulkin,Martin Eklund,Manolis Kogevinas,Javier Llorca,Gemma Castaño-Vinyals,Kathryn L. Penney,Meir J. Stampfer,Jong Y. Park,Thomas A. Sellers,Hui Yi Lin,Janet L. Stanford,Janet L. Stanford,Cezary Cybulski,Dominika Wokołorczyk,Jan Lubinski,Elaine A. Ostrander,Milan S. Geybels,Børge G. Nordestgaard,Sune F. Nielsen,Maren Weischer,Rasmus Bisbjerg,Martin Andreas Røder,Peter Iversen,Hermann Brenner,Katarina Cuk,Bernd Holleczek,Christiane Maier,Manuel Luedeke,Thomas J. Schnoeller,Jeri Kim,Christopher J. Logothetis,Esther M. John,Esther M. John,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Marta Cardoso,Susan L. Neuhausen,Linda Steele,Yuan Chun Ding,Kim De Ruyck,Gert De Meerleer,Piet Ost,Azad Hassan Abdul Razack,Jasmine Lim,Soo Hwang Teo,Daniel W. Lin,Daniel W. Lin,Lisa F. Newcomb,Lisa F. Newcomb,Davor Lessel,Marija Gamulin,Tomislav Kuliš,Radka Kaneva,Nawaid Usmani,Nawaid Usmani,Sandeep Singhal,Sandeep Singhal,Chavdar Slavov,Vanio Mitev,Matthew Parliament,Matthew Parliament,Frank Claessens,Steven Joniau,Thomas Van den Broeck,Samantha E.T. Larkin,Paul A. Townsend,Claire Aukim-Hastie,Manuela Gago Dominguez,Jose Esteban Castelao,Maria Elena Martinez,Monique J. Roobol,Guido Jenster,Ron H.N. van Schaik,Florence Menegaux,Thérèse Truong,Yves Akoli Koudou,Jianfeng Xu,Kay-Tee Khaw,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hardev Pandha,Agnieszka Michael,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Sara Lindström,Constance Turman,Jing Ma,David J. Hunter,Elio Riboli,A. Siddiq,Federico Canzian,Laurence N. Kolonel,Loic Le Marchand,Robert N. Hoover,Mitchell J. Machiela,Zuxi Cui,Peter Kraft,Christopher I. Amos,David V. Conti,Douglas F. Easton,Fredrik Wiklund,Stephen J. Chanock,Brian E. Henderson,Zsofia Kote-Jarai,Christopher A. Haiman,Rosalind A. Eeles +207 more
TL;DR: A large meta-analysis combining genome-wide and custom high-density genotyping array data identifies 63 new susceptibility loci for prostate cancer, enhancing fine-mapping efforts and providing insights into the underlying biology of PrCa1.
Journal ArticleDOI
Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy
Alain Ravaud,Robert J. Motzer,Hardev Pandha,Daniel J. George,Allan J. Pantuck,Anup Patel,Yen-Hwa Chang,Bernard Escudier,F. Donskov,Ahmed Magheli,Giacomo Cartenì,Brigitte Laguerre,Piotr Tomczak,Jan Breza,Paola Gerletti,Mariajose Lechuga,Xun Lin,Jean-Francois Martini,Krishnan Ramaswamy,Michelle Casey,Michael Staehler,Jean-Jacques Patard +21 more
TL;DR: Among patients with locoregional clear-cell renal-cell carcinoma at high risk for tumor recurrence after nephrectomy, the median duration of disease-free survival was significantly longer in the sunitinib group than in the placebo group, at a cost of a higher rate of toxic events.
Journal ArticleDOI
A Phase I Study of OncoVEXGM-CSF, a Second-Generation Oncolytic Herpes Simplex Virus Expressing Granulocyte Macrophage Colony-Stimulating Factor
Jennifer C.C. Hu,Robert S. Coffin,Ceri J. Davis,Nicola J. Graham,Natasha Groves,Peter J. Guest,Kevin J. Harrington,Nicholas D. James,Colin Love,Iain A. McNeish,Louise C. Medley,Agnieszka Michael,Christopher M. Nutting,Hardev Pandha,Claire A. Shorrock,Julie Simpson,Jan Steiner,Neil Steven,Dennis Wright,R. Charles Coombes +19 more
TL;DR: Onco VEXGM-CSF is well tolerated and can be safely administered using the multidosing protocol described, and evidence of an antitumor effect was seen.
Journal ArticleDOI
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
Ali Amin Al Olama,Zsofia Kote-Jarai,Sonja I. Berndt,David V. Conti,Fredrick R. Schumacher,Ying Han,Sara Benlloch,Dennis J. Hazelett,Zhaoming Wang,Ed Saunders,Daniel Leongamornlert,Sara Lindström,Sara Jugurnauth-Little,Tokhir Dadaev,Malgorzata Tymrakiewicz,Daniel O. Stram,Kristin A. Rand,Peggy Wan,Alex Stram,Xin Sheng,Loreall Pooler,Karen Park,Lucy Xia,Jonathan Tyrer,Laurence N. Kolonel,Loic Le Marchand,Robert N. Hoover,Mitchell J. Machiela,Merideth Yeager,Laurie Burdette,Charles C. Chung,Amy K. Hutchinson,Kai Yu,Chee Goh,Mahbubl Ahmed,Koveela Govindasami,Michelle Guy,Teuvo L.J. Tammela,Anssi Auvinen,Tiina Wahlfors,Johanna Schleutker,Tapio Visakorpi,Katri A. Leinonen,Jianfeng Xu,Markus Aly,Jenny L Donovan,Ruth C. Travis,Timothy J. Key,Afshan Siddiq,Federico Canzian,Kay-Tee Khaw,Atsushi Takahashi,Michiaki Kubo,Paul D.P. Pharoah,Nora Pashayan,Maren Weischer,Børge G. Nordestgaard,Sune F. Nielsen,Peter Klarskov,Martin Andreas Røder,Peter Iversen,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Janet L. Stanford,Janet L. Stanford,Suzanne Kolb,Sarah K. Holt,Beatrice S. Knudsen,Antonio Hurtado Coll,Susan M. Gapstur,W. Ryan Diver,Victoria L. Stevens,Christiane Maier,Manuel Luedeke,Kathleen Herkommer,Antje E. Rinckleb,Sara S. Strom,Curtis A. Pettaway,Edward D. Yeboah,Edward D. Yeboah,Yao Tettey,Yao Tettey,Richard B. Biritwum,Richard B. Biritwum,Andrew A. Adjei,Andrew A. Adjei,Evelyn Tay,Evelyn Tay,Ann Truelove,Shelley Niwa,Anand P. Chokkalingam,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Cezary Cybulski,Dominika Wokołorczyk,Wojciech Kluźniak,Jong Y. Park,Thomas A. Sellers,Hui-Yi Lin,William B. Isaacs,Alan W. Partin,Hermann Brenner,Aida Karina Dieffenbach,Christa Stegmaier,Constance Chen,Edward Giovannucci,Jing Ma,Meir J. Stampfer,Kathryn L. Penney,Lorelei A. Mucci,Esther M. John,Esther M. John,Sue A. Ingles,Rick A. Kittles,Adam B. Murphy,Hardev Pandha,Agnieszka Michael,Andrzej M. Kierzek,William J. Blot,Lisa B. Signorello,Wei Zheng,Demetrius Albanes,Jarmo Virtamo,Stephanie J. Weinstein,Barbara Nemesure,John D. Carpten,Cristina Leske,Suh-Yuh Wu,Anselm Hennis,Anselm Hennis,Adam S. Kibel,Benjamin A. Rybicki,Christine Neslund-Dudas,Ann W. Hsing,Ann W. Hsing,Lisa Chu,Lisa Chu,Phyllis J. Goodman,Eric A. Klein,S. Lilly Zheng,Jyotsna Batra,Judith A. Clements,Amanda B. Spurdle,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Sofia Maia,Chavdar Slavov,Radka Kaneva,Vanio Mitev,John S. Witte,Graham Casey,Elizabeth M. Gillanders,Daniella Seminara,Elio Riboli,Freddie C. Hamdy,Gerhard A. Coetzee,Qiyuan Li,Matthew L. Freedman,David J. Hunter,Kenneth Muir,Kenneth Muir,Henrik Grönberg,David E. Neal,David E. Neal,Melissa C. Southey,Graham G. Giles,Graham G. Giles,Gianluca Severi,Gianluca Severi,Michael B. Cook,Hidewaki Nakagawa,Fredrik Wiklund,Peter Kraft,Stephen J. Chanock,Brian E. Henderson,Douglas F. Easton,Rosalind A. Eeles,Christopher A. Haiman +179 more
TL;DR: These findings provide new regions for investigation into the pathogenesis of prostate cancer and demonstrate the usefulness of combining ancestrally diverse populations to discover risk loci for disease.
Journal ArticleDOI
The role of HOX genes in normal hematopoiesis and acute leukemia.
TL;DR: This review covers the current understanding of the role of HOX genes in normal hematopoiesis, AML and ALL, with particular emphasis on the similarities and differences ofHOX function in these contexts, their hematoietic downstream gene targets and implications for therapy.