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Deborah E. Dobson
Researcher at Washington University in St. Louis
Publications - 34
Citations - 3715
Deborah E. Dobson is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Gene & Lipophosphoglycan. The author has an hindex of 23, co-authored 33 publications receiving 3491 citations. Previous affiliations of Deborah E. Dobson include Harvard University & Boston University.
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Journal ArticleDOI
The genome of the kinetoplastid parasite, Leishmania major.
Alasdair Ivens,Christopher S. Peacock,Elizabeth A. Worthey,Lee Murphy,Gautam Aggarwal,Matthew Berriman,Ellen Sisk,Marie-Adèle Rajandream,Ellen Adlem,Rita Aert,Atashi Anupama,Zina Apostolou,Philip Attipoe,Nathalie Bason,Christopher Bauser,Alfred Beck,Stephen M. Beverley,Gabriella Bianchettin,K. Borzym,G. Bothe,Carlo V. Bruschi,Carlo V. Bruschi,Matt Collins,Eithon Cadag,Laura Ciarloni,Christine Clayton,Richard M.R. Coulson,Ann Cronin,Angela K. Cruz,Robert L. Davies,Javier G. De Gaudenzi,Deborah E. Dobson,Andreas Duesterhoeft,Gholam Fazelina,Nigel Fosker,Alberto C.C. Frasch,Audrey Fraser,Monika Fuchs,Claudia Gabel,Arlette Goble,André Goffeau,David Harris,Christiane Hertz-Fowler,Helmut Hilbert,David Horn,Yiting Huang,Sven Klages,Andrew J Knights,Michael Kube,Natasha Larke,Lyudmila Litvin,Angela Lord,Tin Louie,Marco A. Marra,David Masuy,Keith R. Matthews,Shulamit Michaeli,Jeremy C. Mottram,Silke Müller-Auer,Heather Munden,Siri Nelson,Halina Norbertczak,Karen Oliver,Susan O'Neil,Martin Pentony,Thomas M. Pohl,Claire Price,Bénédicte Purnelle,Michael A. Quail,Ester Rabbinowitsch,Richard Reinhardt,Michael A. Rieger,Joel Rinta,Johan Robben,Laura Robertson,Jeronimo C. Ruiz,Simon Rutter,David L. Saunders,Melanie Schäfer,Jacquie Schein,David C. Schwartz,Kathy Seeger,Amber Seyler,Sarah Sharp,Heesun Shin,Dhileep Sivam,Rob Squares,Steve Squares,Valentina Tosato,Christy Vogt,Guido Volckaert,Rolf Wambutt,T. Warren,Holger Wedler,John Woodward,Shiguo Zhou,Wolfgang Zimmermann,Deborah F. Smith,Jenefer M. Blackwell,Kenneth Stuart,Kenneth Stuart,Bart Barrell,Peter J. Myler,Peter J. Myler +103 more
TL;DR: The organization of protein-coding genes into long, strand-specific, polycistronic clusters and lack of general transcription factors in the L. major, Trypanosoma brucei, and Tritryp genomes suggest that the mechanisms regulating RNA polymerase II–directed transcription are distinct from those operating in other eukaryotes, although the trypanosomatids appear capable of chromatin remodeling.
Journal ArticleDOI
Adipocyte P2 gene: Developmental expression and homology of 5'-flanking sequences among fat cell-specific genes
TL;DR: The results indicate that the aP2 gene contains sequence information necessary for differentiation-dependent expression in fat cells; common elements shared by adipocyte-specific genes may play a role in this process.
Journal ArticleDOI
Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector.
Natalia S. Akopyants,Nicola Kimblin,Nágila Francinete Costa Secundino,Rachel L. Patrick,Nathan C. Peters,Phillip G. Lawyer,Deborah E. Dobson,Stephen M. Beverley,David L. Sacks +8 more
TL;DR: Evidence is reported that the invertebrate stages of Leishmania are capable of having a sexual cycle consistent with a meiotic process like that described for African trypanosomes, and hybrids were generated that bore full genomic complements from both parents, but kinetoplast DNA maxicircles from one parent.
PLOS Neglected Tropical Diseases
Nicolas Fasel,Haroun Zangger,Asrat Hailu,Chantal Desponds,Natalia S. Akopyants,Deborah E. Dobson,Catherine Ronet,Hashim Ghalib,Stephen M. Beverley +8 more
TL;DR: Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, Bangladesh.
Journal ArticleDOI
Stomach lysozymes of ruminants. I. Distribution and catalytic properties.
TL;DR: A survey of 23 mammalian species reveals that the lysozyme c activity per g of stomach mucosa is many times higher for ruminants and a leaf-eating monkey than for animals lacking a foregut.