G
G. Bothe
Researcher at GATC Biotech
Publications - 9
Citations - 3402
G. Bothe is an academic researcher from GATC Biotech. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 6, co-authored 8 publications receiving 3287 citations.
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Journal ArticleDOI
The genome of the kinetoplastid parasite, Leishmania major.
Alasdair Ivens,Christopher S. Peacock,Elizabeth A. Worthey,Lee Murphy,Gautam Aggarwal,Matthew Berriman,Ellen Sisk,Marie-Adèle Rajandream,Ellen Adlem,Rita Aert,Atashi Anupama,Zina Apostolou,Philip Attipoe,Nathalie Bason,Christopher Bauser,Alfred Beck,Stephen M. Beverley,Gabriella Bianchettin,K. Borzym,G. Bothe,Carlo V. Bruschi,Carlo V. Bruschi,Matt Collins,Eithon Cadag,Laura Ciarloni,Christine Clayton,Richard M.R. Coulson,Ann Cronin,Angela K. Cruz,Robert L. Davies,Javier G. De Gaudenzi,Deborah E. Dobson,Andreas Duesterhoeft,Gholam Fazelina,Nigel Fosker,Alberto C.C. Frasch,Audrey Fraser,Monika Fuchs,Claudia Gabel,Arlette Goble,André Goffeau,David Harris,Christiane Hertz-Fowler,Helmut Hilbert,David Horn,Yiting Huang,Sven Klages,Andrew J Knights,Michael Kube,Natasha Larke,Lyudmila Litvin,Angela Lord,Tin Louie,Marco A. Marra,David Masuy,Keith R. Matthews,Shulamit Michaeli,Jeremy C. Mottram,Silke Müller-Auer,Heather Munden,Siri Nelson,Halina Norbertczak,Karen Oliver,Susan O'Neil,Martin Pentony,Thomas M. Pohl,Claire Price,Bénédicte Purnelle,Michael A. Quail,Ester Rabbinowitsch,Richard Reinhardt,Michael A. Rieger,Joel Rinta,Johan Robben,Laura Robertson,Jeronimo C. Ruiz,Simon Rutter,David L. Saunders,Melanie Schäfer,Jacquie Schein,David C. Schwartz,Kathy Seeger,Amber Seyler,Sarah Sharp,Heesun Shin,Dhileep Sivam,Rob Squares,Steve Squares,Valentina Tosato,Christy Vogt,Guido Volckaert,Rolf Wambutt,T. Warren,Holger Wedler,John Woodward,Shiguo Zhou,Wolfgang Zimmermann,Deborah F. Smith,Jenefer M. Blackwell,Kenneth Stuart,Kenneth Stuart,Bart Barrell,Peter J. Myler,Peter J. Myler +103 more
TL;DR: The organization of protein-coding genes into long, strand-specific, polycistronic clusters and lack of general transcription factors in the L. major, Trypanosoma brucei, and Tritryp genomes suggest that the mechanisms regulating RNA polymerase II–directed transcription are distinct from those operating in other eukaryotes, although the trypanosomatids appear capable of chromatin remodeling.
Journal ArticleDOI
The composite genome of the legume symbiont Sinorhizobium meliloti.
Francis Galibert,Turlough M. Finan,Sharon R. Long,Sharon R. Long,Alfred Pühler,Pia Abola,Frédéric Ampe,Frédérique Barloy-Hubler,Melanie J. Barnett,Anke Becker,P. Boistard,G. Bothe,Marc Boutry,Leah Bowser,Jens Buhrmester,Edouard Cadieu,Delphine Capela,Delphine Capela,Patrick S. G. Chain,Alison Cowie,Ronald W. Davis,Stéphane Dréano,Nancy A. Federspiel,Robert F. Fisher,Stéphanie Gloux,Thérèse Godrie,André Goffeau,Brian Golding,Jérôme Gouzy,Mani Gurjal,Ismael Hernández-Lucas,Andrea Hong,Lucas Huizar,Richard W. Hyman,Ted Jones,Daniel Kahn,Michael L. Kahn,Sue Kalman,David H. Keating,David H. Keating,Ernö Kiss,Caridad Komp,Valerie Lelaure,David Masuy,Curtis J. Palm,Melicent C. Peck,Thomas M. Pohl,Daniel Portetelle,Bénédicte Purnelle,Uwe Ramsperger,Raymond Surzycki,Patricia Thebault,Micheline Vandenbol,Frank-J. Vorhölter,Stefan Weidner,Derek H. Wells,Kim Wong,Kuo-Chen Yeh,Kuo-Chen Yeh,Jacques Batut +59 more
TL;DR: The annotated DNA sequence of the α-proteobacteriumSinorhizobium meliloti, the symbiont of alfalfa, is presented, indicating that all three elements contribute, in varying degrees, to symbiosis and reveals how this genome may have emerged during evolution.
Journal ArticleDOI
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana
Klaus F. X. Mayer,C. Schüller,R. Wambutt,George Murphy,Guido Volckaert,Thomas Pohl,A. Düsterhöft,Willem J. Stiekema,K.-D. Entian,Nancy Terryn,Barbara Harris,Wilhelm Ansorge,Petra Brandt,Leslie A. Grivell,Michael A. Rieger,M. Weichselgartner,V De Simone,B. Obermaier,R. Mache,Mario Müller,M. Kreis,Michel Delseny,Pere Puigdomènech,Martin D. Watson,T. Schmidtheini,B. Reichert,D. Portatelle,Manuel Pérez-Alonso,Marc Boutry,Ian Bancroft,P. Vos,Joerg Hoheisel,Wolfgang Zimmermann,H. Wedler,P. Ridley,S. A. Langham,B. McCullagh,L. Bilham,Johan Robben,J. Van der Schueren,B. Grymonprez,Y. J. Chuang,F. Vandenbussche,M. Braeken,I. Weltjens,Marleen Voet,I. Bastiaens,Rita Aert,E. Defoor,T. Weitzenegger,G. Bothe,U. Ramsperger,H. Hilbert,M. Braun,E. Holzer,A. Brandt,Sander Peters,M. van Staveren,Wim G. Dirkse,P. Mooijman,R. Klein Lankhorst,M. Rose,J. Hauf,P. Kötter,S. Berneiser,S. Hempel,M. Feldpausch,S. Lamberth,H. Van den Daele,A. De Keyser,C. Buysshaert,J. Gielen,R. Villarroel,R. De Clercq,M. Van Montagu,Jane Rogers,A. Cronin,Michael A. Quail,S. Bray-Allen,L. Clark,J. Doggett,S. Hall,M. Kay,Nicola Lennard,K. McLay,R. Mayes,A. Pettett,Marie-Adèle Rajandream,M. Lyne,Vladimir Benes,S. Rechmann,D. Borkova,H. Blöcker,M. Scharfe,M. Grimm,T. H. Löhnert,S. Dose,M. de Haan,A.C. Maarse,M. Schäfer,S Müller-Auer,C. Gabel,M. Fuchs,Berthold Fartmann,K. Granderath,D. Dauner,A. Herzl,Sindy Neumann,Anagnostis Argiriou,D. Vitale,Rosario Liguori,E. Piravandi,O. Massenet,F. Quigley,G. Clabauld,A. Mündlein,R. Felber,S. Schnabl,R. Hiller,W. Schmidt,A. Lecharny,S. Aubourg,F. Chefdor,R. Cooke,C. Berger,A. Montfort,Elena Casacuberta,T. Gibbons,N. Weber,Micheline Vandenbol,M. D. Bargues,Javier Terol,A. Torres,A Perez-Perez,Bénédicte Purnelle,E. Bent,S. Johnson,D. Tacon,T. Jesse,Leo Heijnen,S. Schwarz,Patrik Scholler,Steffen Heber,P. Francs,C. Bielke,Dmitrij Frishman,D. Haase,Kai Lemcke,Hans-Werner Mewes,S. Stocker,P. Zaccaria,Michael W. Bevan,Richard K. Wilson,M. de la Bastide,K. Habermann,L. Parnell,Neilay Dedhia,L. Gnoj,K. Schutz,E. Huang,Lori Spiegel,M. Sehkon,Joseph A. Murray,P. Sheet,Matt Cordes,J. Abu-Threideh,T. Stoneking,Joelle Kalicki,Tina Graves,G. Harmon,Jennifer Edwards,P. Latreille,Laura Courtney,J. Cloud,A. Abbott,Kelsi Scott,David W. Johnson,Patrick Minx,David Bentley,Bob Fulton,N. Miller,T. Greco,K. Kemp,Jason B. Kramer,Lucinda Fulton,Elaine R. Mardis,Mike Dante,Kymberlie H. Pepin,LaDeana W. Hillier,Joanne O. Nelson,John Spieth,E. Ryan,S. Andrews,C. Geisel,Dan Layman,Hui Du,Johar Ali,A. Berghoff,K. Jones,K. Drone,M. Cotton,Corinne E. Joshu,B. Antonoiu,M. Zidanic,Cindy Strong,H. Sun,B. Lamar,C. Yordan,P. Ma,P. Ma,J. Zhong,J. Zhong,R. Preston,D. Vil,M. Shekher,A. Matero,R. Shah,I'k. Swaby,A. O'Shaughnessy,M. Rodriguez,J. Hoffman,S. Till,S. Granat,Nadim Shohdy,A. Hasegawa,Abdul Hameed,M. Lodhi,A. Johnson,A. Johnson,Ellson Y. Chen,Ellson Y. Chen,Marco A. Marra,Robert A. Martienssen,W. R. McCombie +233 more
TL;DR: Analysis of 17.38 megabases of unique sequence, representing about 17% of the Arabidopsis genome, reveals 3,744 protein coding genes, 81 transfer RNAs and numerous repeat elements.
Journal ArticleDOI
Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021.
Delphine Capela,Frédérique Barloy-Hubler,Jérôme Gouzy,G. Bothe,Frédéric Ampe,Jacques Batut,P. Boistard,Anke Becker,Marc Boutry,Edouard Cadieu,Stéphane Dréano,Stéphanie Gloux,Thérèse Godrie,André Goffeau,Daniel Kahn,Ernö Kiss,Valerie Lelaure,David Masuy,Thomas Pohl,Daniel Portetelle,Alfred Pühler,Bénédicte Purnelle,Ulf Ramsperger,Clotilde Renard,Patricia Thebault,Micheline Vandenbol,Stefan Weidner,Francis Galibert +27 more
TL;DR: The presence in this replicon of a large number of nucleotide cyclases with a peculiar structure, as well as of genes homologous to virulence determinants of animal and plant pathogens, opens perspectives in the study of this bacterium both as a free-living soil microorganism and as a plant symbiont.
Journal ArticleDOI
The Complete DNA Sequence of the Ectocarpus siliculosus Virus EsV-1 Genome
TL;DR: The EsV-1 genome is the largest viral DNA sequenced to date and contains components of a surprisingly complex signal transduction system with six different hybrid histidine protein kinases and four putative serine/threonineprotein kinases.