M
Michael Kube
Researcher at Max Planck Society
Publications - 88
Citations - 10565
Michael Kube is an academic researcher from Max Planck Society. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 51, co-authored 81 publications receiving 9897 citations.
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Journal ArticleDOI
The genome of the kinetoplastid parasite, Leishmania major.
Alasdair Ivens,Christopher S. Peacock,Elizabeth A. Worthey,Lee Murphy,Gautam Aggarwal,Matthew Berriman,Ellen Sisk,Marie-Adèle Rajandream,Ellen Adlem,Rita Aert,Atashi Anupama,Zina Apostolou,Philip Attipoe,Nathalie Bason,Christopher Bauser,Alfred Beck,Stephen M. Beverley,Gabriella Bianchettin,K. Borzym,G. Bothe,Carlo V. Bruschi,Carlo V. Bruschi,Matt Collins,Eithon Cadag,Laura Ciarloni,Christine Clayton,Richard M.R. Coulson,Ann Cronin,Angela K. Cruz,Robert L. Davies,Javier G. De Gaudenzi,Deborah E. Dobson,Andreas Duesterhoeft,Gholam Fazelina,Nigel Fosker,Alberto C.C. Frasch,Audrey Fraser,Monika Fuchs,Claudia Gabel,Arlette Goble,André Goffeau,David Harris,Christiane Hertz-Fowler,Helmut Hilbert,David Horn,Yiting Huang,Sven Klages,Andrew J Knights,Michael Kube,Natasha Larke,Lyudmila Litvin,Angela Lord,Tin Louie,Marco A. Marra,David Masuy,Keith R. Matthews,Shulamit Michaeli,Jeremy C. Mottram,Silke Müller-Auer,Heather Munden,Siri Nelson,Halina Norbertczak,Karen Oliver,Susan O'Neil,Martin Pentony,Thomas M. Pohl,Claire Price,Bénédicte Purnelle,Michael A. Quail,Ester Rabbinowitsch,Richard Reinhardt,Michael A. Rieger,Joel Rinta,Johan Robben,Laura Robertson,Jeronimo C. Ruiz,Simon Rutter,David L. Saunders,Melanie Schäfer,Jacquie Schein,David C. Schwartz,Kathy Seeger,Amber Seyler,Sarah Sharp,Heesun Shin,Dhileep Sivam,Rob Squares,Steve Squares,Valentina Tosato,Christy Vogt,Guido Volckaert,Rolf Wambutt,T. Warren,Holger Wedler,John Woodward,Shiguo Zhou,Wolfgang Zimmermann,Deborah F. Smith,Jenefer M. Blackwell,Kenneth Stuart,Kenneth Stuart,Bart Barrell,Peter J. Myler,Peter J. Myler +103 more
TL;DR: The organization of protein-coding genes into long, strand-specific, polycistronic clusters and lack of general transcription factors in the L. major, Trypanosoma brucei, and Tritryp genomes suggest that the mechanisms regulating RNA polymerase II–directed transcription are distinct from those operating in other eukaryotes, although the trypanosomatids appear capable of chromatin remodeling.
Journal ArticleDOI
Genome analysis of the platypus reveals unique signatures of evolution
Wesley C. Warren,LaDeana W. Hillier,Jennifer A. Marshall Graves,Ewan Birney,Chris P. Ponting,Frank Grützner,Katherine Belov,Webb Miller,Laura Clarke,Asif T. Chinwalla,Shiaw Pyng Yang,Andreas Heger,Devin P. Locke,Pat Miethke,Paul D. Waters,Frédéric Veyrunes,Frédéric Veyrunes,Lucinda Fulton,Bob Fulton,Tina Graves,John W. Wallis,Xose S. Puente,Carlos López-Otín,Gonzalo R. Ordóñez,Evan E. Eichler,Lin Chen,Ze Cheng,Janine E. Deakin,Amber E. Alsop,Katherine Thompson,Patrick J. Kirby,Anthony T. Papenfuss,Matthew Wakefield,Tsviya Olender,Doron Lancet,Gavin A. Huttley,Arian F.A. Smit,Andrew J Pask,Peter Temple-Smith,Peter Temple-Smith,Mark A. Batzer,Jerilyn A. Walker,Miriam K. Konkel,Robert S. Harris,Camilla M. Whittington,Emily S. W. Wong,Neil J. Gemmell,Emmanuel Buschiazzo,Iris M. Vargas Jentzsch,Angelika Merkel,Juergen Schmitz,Anja Zemann,Gennady Churakov,Jan Ole Kriegs,Juergen Brosius,Elizabeth P. Murchison,Ravi Sachidanandam,Carly Smith,Gregory J. Hannon,Enkhjargal Tsend-Ayush,Daniel McMillan,Rosalind Attenborough,Willem Rens,Malcolm A. Ferguson-Smith,Christophe Lefevre,Christophe Lefevre,Julie A. Sharp,Kevin R. Nicholas,David A. Ray,Michael Kube,Richard Reinhardt,Thomas H. Pringle,James Taylor,Russell C. Jones,Brett Nixon,Jean Louis Dacheux,Hitoshi Niwa,Yoko Sekita,Xiaoqiu Huang,Alexander Stark,Pouya Kheradpour,Manolis Kellis,Paul Flicek,Yuan Chen,Caleb Webber,Ross C. Hardison,Joanne O. Nelson,Kym Hallsworth-Pepin,Kim D. Delehaunty,Chris Markovic,Patrick Minx,Yucheng Feng,Colin Kremitzki,Makedonka Mitreva,Jarret Glasscock,Todd Wylie,Patricia Wohldmann,Prathapan Thiru,Michael N. Nhan,Craig Pohl,Scott M. Smith,Shunfeng Hou,Marilyn B. Renfree,Elaine R. Mardis,Richard K. Wilson +104 more
TL;DR: It is found that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypUS biology.
Journal ArticleDOI
Complete genome sequence of the marine planctomycete Pirellula sp. strain 1.
Frank Oliver Glöckner,Michael Kube,Margit Bauer,Hanno Teeling,Thierry Lombardot,Wolfgang Ludwig,Dörte Gade,Alfred Beck,K. Borzym,Katja Heitmann,Ralf Rabus,Heinz Schlesner,Rudolf Amann,Richard Reinhardt +13 more
TL;DR: Phylogenetic analysis of all relevant markers clearly affiliates the Planctomycetales to the domain Bacteria as a distinct phylum, but a deepest branching is not supported by the authors' analyses.
Journal ArticleDOI
Phylogenomic analyses unravel annelid evolution
Torsten H. Struck,Christiane Paul,Natascha Hill,Stefanie Hartmann,Christoph Hösel,Michael Kube,Bernhard Lieb,Achim Meyer,Ralph Tiedemann,Günter Purschke,Christoph Bleidorn,Christoph Bleidorn +11 more
TL;DR: It is shown that phylogenomic analyses of 34 annelid taxa, using 47,953 amino acid positions, recovered a well-supported phylogeny with strong support for major splits and Ancestral character trait reconstructions indicate that these clades show adaptation to either an errant or a sedentary lifestyle.
Journal ArticleDOI
A conspicuous nickel protein in microbial mats that oxidize methane anaerobically
Martin Krüger,Anke Meyerdierks,Frank Oliver Glöckner,Rudolf Amann,Friedrich Widdel,Michael Kube,Richard Reinhardt,Jörg Kahnt,Reinhard Böcher,Rudolf K. Thauer,Seigo Shima +10 more
TL;DR: The abundance of the nickel protein (7% of extracted proteins) in the mat suggests an important role in AOM, and similarities to methyl-coenzyme M reductase from methanogenic archaea are revealed.