D
Deepti Pant
Researcher at Beth Israel Deaconess Medical Center
Publications - 4
Citations - 422
Deepti Pant is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: White adipose tissue & Stromal cell. The author has an hindex of 2, co-authored 4 publications receiving 92 citations.
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Journal ArticleDOI
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
Toni Delorey,Carly G. K. Ziegler,Graham Heimberg,Rachelly Normand,Yiming Yang,Yiming Yang,Asa Segerstolpe,Domenic Abbondanza,Stephen J. Fleming,Ayshwarya Subramanian,Daniel T. Montoro,Karthik A. Jagadeesh,Kushal K. Dey,Pritha Sen,Michal Slyper,Yered Pita-Juárez,Devan Phillips,Jana Biermann,Zohar Bloom-Ackermann,Nikolaos Barkas,Andrea Ganna,Andrea Ganna,James Gomez,Johannes C. Melms,Igor Katsyv,Erica Normandin,Erica Normandin,Pourya Naderi,Pourya Naderi,Yury Popov,Yury Popov,Siddharth S. Raju,Siddharth S. Raju,Sebastian Niezen,Sebastian Niezen,Linus T.-Y. Tsai,Katherine J. Siddle,Katherine J. Siddle,Malika Sud,Victoria M. Tran,Shamsudheen K. Vellarikkal,Shamsudheen K. Vellarikkal,Yiping Wang,Liat Amir-Zilberstein,Deepak Atri,Deepak Atri,Joseph M. Beechem,Olga R. Brook,Jonathan H. Chen,Jonathan H. Chen,Prajan Divakar,Phylicia Dorceus,Jesse M. Engreitz,Jesse M. Engreitz,Adam Essene,Donna M. Fitzgerald,Robin Fropf,Steven Gazal,Joshua Gould,John Grzyb,Tyler Harvey,Jonathan L. Hecht,Jonathan L. Hecht,Tyler Hether,Judit Jané-Valbuena,Michael Leney-Greene,Hui Ma,Hui Ma,Cristin McCabe,Daniel E. McLoughlin,Eric M. Miller,Christoph Muus,Christoph Muus,Mari Niemi,Robert F. Padera,Robert F. Padera,Robert F. Padera,Liuliu Pan,Deepti Pant,Carmel Pe’er,Jenna Pfiffner-Borges,Christopher J. Pinto,Jacob Plaisted,Jason Reeves,Marty Ross,Melissa Rudy,Erroll H. Rueckert,Michelle Siciliano,Alexander Sturm,Ellen Todres,Avinash Waghray,Sarah Warren,Shuting Zhang,Daniel R. Zollinger,Lisa A. Cosimi,Rajat M. Gupta,Rajat M. Gupta,Nir Hacohen,Nir Hacohen,Hanina Hibshoosh,Winston Hide,Alkes L. Price,Jayaraj Rajagopal,Purushothama Rao Tata,Stefan Riedel,Stefan Riedel,Gyongyi Szabo,Gyongyi Szabo,Gyongyi Szabo,Timothy L. Tickle,Patrick T. Ellinor,Deborah T. Hung,Deborah T. Hung,Pardis C. Sabeti,Richard M. Novak,Robert S. Rogers,Robert S. Rogers,Donald E. Ingber,Donald E. Ingber,Donald E. Ingber,Z. Gordon Jiang,Z. Gordon Jiang,Dejan Juric,Mehrtash Babadi,Samouil L. Farhi,Benjamin Izar,James R. Stone,Ioannis S. Vlachos,Isaac H. Solomon,Orr Ashenberg,Caroline B. M. Porter,Bo Li,Bo Li,Alex K. Shalek,Alexandra-Chloé Villani,Orit Rozenblatt-Rosen,Orit Rozenblatt-Rosen,Aviv Regev +137 more
TL;DR: In this article, single-cell analysis of lung, heart, kidney and liver autopsy samples shows the molecular and cellular changes and immune response resulting from severe SARS-CoV-2 infection.
Posted ContentDOI
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2
Toni Delorey,Carly G. K. Ziegler,Graham Heimberg,Rachelly Normand,Yiming Yang,Yiming Yang,Asa Segerstolpe,Domenic Abbondanza,Stephen J. Fleming,Ayshwarya Subramanian,Daniel T. Montoro,Karthik A. Jagadeesh,Kushal K. Dey,Pritha Sen,Michal Slyper,Yered Pita-Juárez,Devan Phillips,Zohar Bloom-Ackermann,Nick Barkas,Andrea Ganna,Andrea Ganna,James Gomez,Erica Normandin,Erica Normandin,Pourya Naderi,Pourya Naderi,Yury Popov,Yury Popov,Siddharth S. Raju,Siddharth S. Raju,Sebastian Niezen,Sebastian Niezen,Linus T.-Y. Tsai,Katherine J. Siddle,Katherine J. Siddle,Malika Sud,Victoria M. Tran,Shamsudheen K. Vellarikkal,Shamsudheen K. Vellarikkal,Liat Amir-Zilberstein,Joseph M. Beechem,Olga R. Brook,Jonathan H. Chen,Jonathan H. Chen,Prajan Divakar,Phylicia Dorceus,Jesse M. Engreitz,Jesse M. Engreitz,Adam Essene,Donna M. Fitzgerald,Robin Fropf,Steven Gazal,Joshua Gould,Tyler Harvey,Jonathan L. Hecht,Jonathan L. Hecht,Tyler Hether,Judit Jané-Valbuena,Michael Leney-Greene,Hui Ma,Hui Ma,Cristin McCabe,Daniel E. McLoughlin,Eric M. Miller,Christoph Muus,Christoph Muus,Mari Niemi,Robert F. Padera,Robert F. Padera,Robert F. Padera,Liuliu Pan,Deepti Pant,Jenna Pfiffner-Borges,Christopher J. Pinto,Jason Reeves,Marty Ross,Melissa Rudy,Erroll H. Rueckert,Michelle Siciliano,Alexander Sturm,Ellen Todres,Avinash Waghray,Sarah Warren,Shuting Zhang,Dan Zollinger,Lisa A. Cosimi,Rajat M. Gupta,Rajat M. Gupta,Nir Hacohen,Nir Hacohen,Winston Hide,Alkes L. Price,Jayaraj Rajagopal,Purushothama Rao Tata,Stefan Riedel,Stefan Riedel,Gyongyi Szabo,Gyongyi Szabo,Gyongyi Szabo,Timothy L. Tickle,Deborah T. Hung,Deborah T. Hung,Pardis C. Sabeti,Richard M. Novak,Robert S. Rogers,Robert S. Rogers,Donald E. Ingber,Donald E. Ingber,Donald E. Ingber,Z. Gordon Jiang,Z. Gordon Jiang,Dejan Juric,Mehrtash Babadi,Samouil L. Farhi,James R. Stone,Ioannis S. Vlachos,Isaac H. Solomon,Orr Ashenberg,Caroline B. M. Porter,Bo Li,Bo Li,Alex K. Shalek,Alexandra-Chloé Villani,Orit Rozenblatt-Rosen,Orit Rozenblatt-Rosen,Aviv Regev +125 more
TL;DR: In this paper, the authors used single-cell and single-nucleus RNA-Seq of lung, kidney, liver, and heart tissues collected during the clinical autopsy of 17 individuals who succumbed to the SARS-CoV-2 pandemic.
Journal ArticleDOI
PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.
Maynara L. Andrade,Gustavo R. Gilio,Luiz Augusto Perandini,Albert S. Peixoto,Mayara Franzoi Moreno,Érique Castro,Tiago E. Oliveira,Thayna S. Vieira,Milene Ortiz-Silva,Caroline A. Thomazelli,Adriano B. Chaves-Filho,Thiago Belchior,Patricia Chimin,Juliana Magdalon,Rachael Ivison,Deepti Pant,Linus T.-Y. Tsai,Marcos Yukio Yoshinaga,Sayuri Miyamoto,William T. Festuccia +19 more
TL;DR: In this paper, the authors investigated the involvement of rapamycin complex 1 (mTORC1) as a mediator of the actions of the PPARγ ligand rosiglitazone in subcutaneous inguinal white adipose tissue (iWAT) mass, endocrine function, lipidome, transcriptome and branched chain amino acid (BCAA) metabolism.
Posted ContentDOI
A single cell atlas of human and mouse white adipose tissue
Margo P. Emont,Margo P. Emont,Christopher Jacobs,Christopher Jacobs,Adam Essene,Deepti Pant,Danielle Tenen,Danielle Tenen,Georgia Colleluori,Angelica Di Vincenzo,Anja Jørgensen,Hesam Dashti,Adam Stefek,Elizabeth McGonagle,Sophie Strobel,Samantha Laber,Saaket Agrawal,Saaket Agrawal,Gregory P. Westcott,Amrita Kar,Amrita Kar,Molly L. Veregge,Anton Gulko,Harini Srinivasan,Harini Srinivasan,Zachary Kramer,Eleanna De Filippis,Erin Merkel,Jennifer Ducie,Christopher G. Boyd,William Gourash,Anita P. Courcoulas,Samuel J. Lin,Bernard T. Lee,Donald Morris,Adam M. Tobias,Amit Khera,Amit Khera,Melina Claussnitzer,Melina Claussnitzer,Tune H. Pers,Antonio Giordano,Orr Ashenberg,Aviv Regev,Aviv Regev,Aviv Regev,Linus Tsai,Linus Tsai,Linus Tsai,Evan D. Rosen,Evan D. Rosen,Evan D. Rosen +51 more
TL;DR: In this article, the authors provide detailed cellular atlases of human and murine subcutaneous and visceral white fat at single cell resolution across a range of body weight, identifying subpopulations of adipocytes, adipose stem and progenitor cells (ASPCs), vascular, and immune cells.