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Derek J. Smith
Researcher at University of Cambridge
Publications - 135
Citations - 18468
Derek J. Smith is an academic researcher from University of Cambridge. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 54, co-authored 121 publications receiving 16430 citations. Previous affiliations of Derek J. Smith include Erasmus University Medical Center & Texas Instruments.
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Journal ArticleDOI
Influenza virus infection history shapes antibody responses to influenza vaccination
Maria Auladell,Hoang Vu Mai Phuong,Le Quynh Mai,Yeu-Yang Tseng,Louise A. Carolan,S. H. Wilks,Pham Quang Thai,David Price,Nguyen Thanh Duong,Nguyen Le Khang Hang,Le Thi Thanh,Nguyen Thi Hong Thuong,Tran Duong,Nguyen Thi Ngoc Diep,Vu Thi Ngoc Bich,Arseniy Khvorov,Luca Hensen,Tran Nhu Duong,Katherine Kedzierska,Dang Duc Anh,Heiman F. L. Wertheim,Scott D. Boyd,Kim L. Good-Jacobson,Derek J. Smith,Ian G. Barr,Sheena G. Sullivan,H. Rogier van Doorn,Annette Fox +27 more
TL;DR: The authors investigated the effect of prior influenza A(H3N2) infection on hemagglutinin-inhibiting antibody responses induced by a locally available influenza vaccine administered in November 2016.
Proceedings ArticleDOI
A random walk in Hamming space
Derek J. Smith,P. Stanford +1 more
TL;DR: The scatter code is described, a new technique for mapping sensor data into a form suitable for processing by associative neural networks that has a practically limitless number of points and the ability to control the radius of association in the mapped sensor data.
Posted ContentDOI
SARS-CoV-2 Variant Vaccine Boosters Trial: Preliminary Analyses
Angela Branche,Nadine Rouphael,David Diemert,Ann R. Falsey,Cecilia Losada,Lindsey R. Baden,Sharon E. Frey,Jennifer A. Whitaker,Susan J. Little,Evan J. Anderson,Emmanuel B. Walter,Richard M. Nowak,Richard E. Rupp,Lisa A. Jackson,T. Mariya Babu,Angelica Kottkamp,Anne F Luetkemeyer,Lilly Cheng Immergluck,Rachel M. Presti,Martin Bäcker,Patricia L. Winokur,Siham Mahgoub,Paul A. Goepfert,Dahlene N. Fusco,Elissa Malkin,Jeffrey M. Bethony,Edward E. Walsh,Daniel S. Graciaa,Hady Samaha,Amy C. Sherman,Stephen R. Walsh,Getahun Abate,Zacharoula Oikonomopoulou,Hana M. El Sahly,Thomas C S Martin,Christina A. Rostad,M. Smith,Benjamin G Ladner,Laura K. Porterfield,Maya Dunstan,Anna Wald,Tamia Davis,Robert L. Atmar,Mark J. Mulligan,Kirsten E. Lyke,Christine M. Posavad,Mary Meagher,David S. Stephens,Kathleen M. Neuzil,Kuleni Abebe,Heather Hill,Jim Albert,Teri Lewis,Lisa Giebeig,Amanda Eaton,Antonia Netzl,S. H. Wilks,Sina Türeli,Mamodikoe Makhene,Sonja Crandon,Marina S. Lee,Seema U Nayak,David C. Montefiori,Mat Makowski,Derek J. Smith,Paul C. Roberts,John H. Beigel +66 more
TL;DR: Safety and immunogenicity of SARS-CoV-2 variant vaccines were safe and well-tolerated and neutralization antibody titers were observed with Omicron-containing vaccines compared to Prototype vaccine and titers against Omicrons BA.1+Prototype vaccines.
Journal ArticleDOI
Antigenic evolution of dengue viruses over 20 years.
Leah C. Katzelnick,Leah C. Katzelnick,Ana Coello Escoto,Ana Coello Escoto,Angkana T. Huang,Bernardo García-Carreras,Nayeem Chowdhury,Irina Maljkovic Berry,Chris Chavez,Philippe Buchy,Veasna Duong,Philippe Dussart,Gregory D. Gromowski,Louis R. Macareo,Butsaya Thaisomboonsuk,Stefan Fernandez,Derek J. Smith,Richard G. Jarman,Stephen S. Whitehead,Henrik Salje,Henrik Salje,Derek A. T. Cummings +21 more
TL;DR: Infection with one of dengue viruses 1 to 4 (DENV1-4) induces protective antibodies against homotypic infection as mentioned in this paper, however, a notable feature of Dengue virus is the ability to use preexisting heter...
Journal ArticleDOI
Influenza B vaccine lineage selection—An optimized trivalent vaccine
Ana Mosterín Höpping,Judith M. Fonville,Judith M. Fonville,Colin A. Russell,Sarah James,Derek J. Smith +5 more
TL;DR: It is shown that some of the benefit of transferring to a quadrivalent vaccine can be captured without the cost of moving to a Quadrivalent Vaccine with an improved trivalent vaccine lineage selection approach.