D
Derek J. Smith
Researcher at University of Cambridge
Publications - 135
Citations - 18468
Derek J. Smith is an academic researcher from University of Cambridge. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 54, co-authored 121 publications receiving 16430 citations. Previous affiliations of Derek J. Smith include Erasmus University Medical Center & Texas Instruments.
Papers
More filters
Patent
Distributed processing memory chip with embedded logic having both data memory and broadcast memory
Shivaling S. Mahant-Shetti,Derek J. Smith,Basavaraj I. Pawate,George R. Doddington,Warren L. Bean,Mark G. Harward,Thomas J. Aton +6 more
TL;DR: Memory chips with data memory (202), embedded logic (206) and broadcast memory (204) for two modes of operation are disclosed in this paper, where the memory chips are organized in a hierarchical manner and include address-associative memory systems.
Journal ArticleDOI
Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses
Colin A. Russell,Terry Jones,Terry Jones,Terry Jones,Ian G. Barr,Nancy J. Cox,Rebecca Garten,V. Gregory,Ian D. Gust,Alan W. Hampson,Alan J. Hay,Aeron C. Hurt,Jan C. de Jong,Anne Kelso,Alexander Klimov,Tsutomu Kageyama,Naomi Komadina,Alan Lapedes,Yi P. Lin,Ana Mosterin,Ana Mosterin,Masatsugu Obuchi,Takato Odagiri,Albert D. M. E. Osterhaus,Guus F. Rimmelzwaan,Michael W. Shaw,Eugene Skepner,Klaus Stöhr,Masato Tashiro,Ron A. M. Fouchier,Derek J. Smith,Derek J. Smith +31 more
TL;DR: The World Health Organization Global Influenza Surveillance Network (WHO GISN) tracks and analyzes the evolution and epidemiology of influenza viruses for the primary purpose of vaccine strain selection and to improve the strain selection process through studies aimed at better understanding virus evolution and Epidemiology.
Journal ArticleDOI
Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding
Salin Chutinimitkul,Sander Herfst,John Steel,Anice C. Lowen,Jianqiang Ye,Debby van Riel,Eefje J. A. Schrauwen,Theo M. Bestebroer,Björn F. Koel,David F. Burke,Kyle H. Sutherland-Cash,Chris S. Whittleston,Colin A. Russell,Colin A. Russell,David J. Wales,Derek J. Smith,Derek J. Smith,Derek J. Smith,Marcel Jonges,Adam Meijer,Marion Koopmans,Guus F. Rimmelzwaan,Thijs Kuiken,Albert D. M. E. Osterhaus,Adolfo García-Sastre,Daniel R. Perez,Ron A. M. Fouchier +26 more
TL;DR: Altered receptor specificity of the virus with D222G thus affected interaction with cells of the human lower respiratory tract, possibly explaining the observed association with enhanced disease in humans.
Journal ArticleDOI
Flavivirus-induced antibody cross-reactivity
Karen L. Mansfield,Karen L. Mansfield,Daniel L. Horton,Daniel L. Horton,Nicholas Johnson,Li Li,Alan D.T. Barrett,Derek J. Smith,Sareen E. Galbraith,Tom Solomon,Anthony R. Fooks,Anthony R. Fooks +11 more
TL;DR: It is evident from these data that notable differences exist between amino acid sequence identity and mapped antigenic relationships within the family Flaviviridae.
Journal ArticleDOI
Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 northern hemisphere season
Ian G. Barr,John W. McCauley,Nancy Cox,Rod S. Daniels,Othmar G. Engelhardt,Keiji Fukuda,Gary Grohmann,Alan Hay,Anne Kelso,Alexander Klimov,Takato Odagiri,Derek J. Smith,Colin A. Russell,Masato Tashiro,Richard J. Webby,John Wood,Zhiping Ye,Wenqing Zhang +17 more
TL;DR: The latest data generated from many sources and the availability of viruses that are suitable for vaccine manufacture are presented, based on the latest data and background to the recommendations for the 2009-2010 Northern Hemisphere influenza vaccine formulation.