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Detlef Weigel
Researcher at Max Planck Society
Publications - 558
Citations - 94360
Detlef Weigel is an academic researcher from Max Planck Society. The author has contributed to research in topics: Arabidopsis & Gene. The author has an hindex of 142, co-authored 516 publications receiving 84670 citations. Previous affiliations of Detlef Weigel include Ludwig Maximilian University of Munich & California Institute of Technology.
Papers
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Journal ArticleDOI
The Rate and Molecular Spectrum of Spontaneous Mutations in Arabidopsis thaliana
Stephan Ossowski,Korbinian Schneeberger,José Ignacio Lucas-Lledó,Norman Warthmann,Richard M. Clark,Ruth G. Shaw,Detlef Weigel,Michael Lynch +7 more
TL;DR: This work searched for de novo spontaneous mutations in the complete nuclear genomes of five Arabidopsis thaliana mutation accumulation lines that had been maintained by single-seed descent for 30 generations, and identified and validated 99 base substitutions and 17 small and large insertions and deletions.
Book
Arabidopsis : a laboratory manual
Detlef Weigel,Jane Glazebrook +1 more
TL;DR: This chapter discusses how to transform Arabidopsis, how to isolate a gene defined by a mutation, and how to study gene function.
Journal ArticleDOI
Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction.
TL;DR: This paper describes the cloning and expression of a Xenopus homolog of Brachyury, Xbra, and shows that expression of Xbra occurs as a result of mesoderm induction in Xenopus, both in Response to the natural signal and in response to the Mesoderm-inducing factors activin A and basic FGF.
Journal ArticleDOI
1,135 Genomes Reveal the Global Pattern of Polymorphism in Arabidopsis thaliana
Carlos Alonso-Blanco,Jorge Andrade,Claude Becker,Felix Bemm,Joy Bergelson,Karsten M. Borgwardt,Jun Cao,Eunyoung Chae,Todd M. Dezwaan,Wei Ding,Joseph R. Ecker,Moises Exposito-Alonso,Ashley Farlow,Joffrey Fitz,Xiangchao Gan,Dominik G. Grimm,Angela M. Hancock,Stefan R. Henz,Svante Holm,Matthew W. Horton,Mike Jarsulic,Randall A. Kerstetter,Arthur Korte,Pamela Korte,Christa Lanz,Cheng-Ruei Lee,Dazhe Meng,Todd P. Michael,Richard Mott,Ni Wayan Muliyati,Thomas Nägele,Matthias Nagler,Viktoria Nizhynska,Magnus Nordborg,Polina Yu. Novikova,F. Xavier Picó,Alexander Platzer,Fernando A. Rabanal,Alex Rodriguez,Beth A. Rowan,Patrice A. Salomé,Karl Schmid,Robert J. Schmitz,Ümit Seren,Felice Gianluca Sperone,Mitchell Sudkamp,Hannes Svardal,Matt M. Tanzer,Donald Todd,Samuel L. Volchenboum,Congmao Wang,George Wang,Xi Wang,Wolfram Weckwerth,Detlef Weigel,Xuefeng Zhou +55 more
TL;DR: Insights into the history of the species and the fine-scale distribution of genetic diversity provide the basis for full exploitation of A. thaliana natural variation through integration of genomes and epigenomes with molecular and non-molecular phenotypes.
Journal ArticleDOI
Whole-genome sequencing of multiple Arabidopsis thaliana populations
Jun Cao,Korbinian Schneeberger,Stephan Ossowski,Stephan Ossowski,Torsten Günther,Sebastian Bender,Joffrey Fitz,Daniel Koenig,Christa Lanz,Oliver Stegle,Christoph Lippert,Xi Wang,Felix Ott,Jonas Müller,Carlos Alonso-Blanco,Karsten M. Borgwardt,Karl Schmid,Detlef Weigel +17 more
TL;DR: The majority of common small-scale polymorphisms as well as many larger insertions and deletions in the A. thaliana pan-genome are described, their effects on gene function, and the patterns of local and global linkage among these variants.