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Dun Xian Tan
Researcher at University of Texas Health Science Center at San Antonio
Publications - 315
Citations - 47893
Dun Xian Tan is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Melatonin & Oxidative stress. The author has an hindex of 117, co-authored 308 publications receiving 42258 citations. Previous affiliations of Dun Xian Tan include University of Texas System & University of Texas at Austin.
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Journal ArticleDOI
Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas
Russel J. Reiter,Sergio Rosales-Corral,Dun Xian Tan,Mei Jie Jou,Mei Jie Jou,Annia Galano,Bing Xu +6 more
TL;DR: Melatonin’s high concentrations and multiple actions as an antioxidant provide potent antioxidant protection to these organelles which are exposed to abundant free radicals, particularly when they are under high oxidative stress conditions.
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Identification of highly elevated levels of melatonin in bone marrow: Its origin and significance
Dun Xian Tan,Lucien C. Manchester,Russel J. Reiter,Wenbo Qi,Ming Zhang,Susan T. Weintraub,Javier Cabrera,Rosa M. Sainz,Juan C. Mayo +8 more
TL;DR: The results indicate that a major portion of the bone marrow's melatonin is of extrapineal origin and may provide on-site protection to reduce oxidative damage to these highly vulnerable hematopoietic cells and may enhance the immune capacity of cells such as lymphocytes.
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Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence
Armando Menendez-Pelaez,Burkhard Poeggeler,Russel J. Reiter,Lornell Barlow-Walden,Marta I. Pablos,Dun Xian Tan +5 more
TL;DR: The results of these studies suggest that melatonin may interact with nuclear proteins and that the indole may have an important function at the nuclear level in a variety of mammalian tissues.
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High levels of melatonin in the seeds of edible plants: Possible function in germ tissue protection
TL;DR: In this paper, the authors examined the seeds of 15 edible plants for the presence of melatonin which was extracted using cold ethanol and found that the highest concentrations of Melatonin were observed in white and black mustard seeds.
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Cardiovascular diseases: protective effects of melatonin.
Sandra Tengattini,Russel J. Reiter,Dun Xian Tan,M. Pilar Terron,Luigi Fabrizio Rodella,Rita Rezzani +5 more
TL;DR: Melatonin attenuates molecular and cellular damages resulting from cardiac ischemia/reperfusion in which destructive free radicals are involved and is involved in the protection against a chronic vascular disease, atherosclerosis.