D
Dun Xian Tan
Researcher at University of Texas Health Science Center at San Antonio
Publications - 315
Citations - 47893
Dun Xian Tan is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Melatonin & Oxidative stress. The author has an hindex of 117, co-authored 308 publications receiving 42258 citations. Previous affiliations of Dun Xian Tan include University of Texas System & University of Texas at Austin.
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Journal ArticleDOI
Melatonin: An Established Antioxidant Worthy of Use in Clinical Trials
Ahmet Korkmaz,Ahmet Korkmaz,Russel J. Reiter,Turgut Topal,Lucien C. Manchester,Sukru Oter,Dun Xian Tan +6 more
TL;DR: Melatonin is a multifunctional indolamine that counteracts virtually all pathophysiologic steps and displays significant beneficial actions against peroxynitrite-induced cellular toxicity, related to melatonin’s antioxidative and antiinflammatory properties.
Journal ArticleDOI
Causes of Oxidative Stress in the Pre- and Perinatal Period
Eloisa Gitto,Russel J. Reiter,Malgorzata Karbownik,Dun Xian Tan,Placido Gitto,Salvatore Barberi,Ignazio Barberi +6 more
TL;DR: Evidence continues to accumulate that oxidative stress is a mediator of endothelial dysfunction and thus contributes to the cardiovascular complications of preeclampsia and may play a role in the pathogenesis of a number of diseases in the newborn.
Applied nutritional investigation Melatonin in walnuts: Influence on levels of melatonin and total antioxidant capacity of blood
TL;DR: In this paper, the authors investigated whether melatonin is present in walnuts (Juglans regia L.) and, if so, tested whether eating walnuts influences melatonin levels and the total antioxidant status of the blood.
Journal ArticleDOI
The changing biological roles of melatonin during evolution: From an antioxidant to signals of darkness, sexual selection and fitness
Dun Xian Tan,Rüdiger Hardeland,Lucien C. Manchester,Sergio D. Paredes,Ahmet Korkmaz,Rosa M. Sainz,Juan C. Mayo,Lorena Fuentes-Broto,Russel J. Reiter +8 more
TL;DR: The changing biological roles of melatonin seem to have evolved from its primary function as an antioxidant, which may indicate senescence in terms of a bio‐clock in many organisms.
Journal ArticleDOI
Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts
TL;DR: Six genes, that is, TDC, TPH, T5H, SNAT, ASMT, and COMT, have been implicated in the synthesis of melatonin in plants, suggesting the presence of multiple pathways.