D
Dun Xian Tan
Researcher at University of Texas Health Science Center at San Antonio
Publications - 315
Citations - 47893
Dun Xian Tan is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Melatonin & Oxidative stress. The author has an hindex of 117, co-authored 308 publications receiving 42258 citations. Previous affiliations of Dun Xian Tan include University of Texas System & University of Texas at Austin.
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Journal ArticleDOI
Melatonin: A novel protective agent against oxidative injury of the ischemic/reperfused heart
Russel J. Reiter,Dun Xian Tan +1 more
TL;DR: This brief review summarizes the recently obtained evidence which illustrates the beneficial effects of the endogenously produced antioxidant, melatonin, in reducing tissue damage and reversing cardiac pathophysiology in models of experimental ischemia/reperfusion in humans.
Journal Article
Medical implications of melatonin: receptor-mediated and receptor-independent actions.
Russel J. Reiter,Dun Xian Tan,Lucien C. Manchester,M. Pilar Terron,Luis J. Flores,S. Koppisepi +5 more
TL;DR: Among the actions of melatonin that are likely receptor independent and that are reviewed herein include its ability to neutralize free radicals which leads to a reduction in cataract formation, reducing oxidative stress due to exposure to hyperbaric hyperoxia, ameliorating hyperthyroidism and abating the toxicity of sepsis and septic shock.
Journal ArticleDOI
Melatonin mediates the regulation of ABA metabolism, free-radical scavenging, and stomatal behaviour in two Malus species under drought stress.
TL;DR: E inducing melatonin production is an important mechanism by which plants can counteract the influence of this abiotic stressor and effectively regulate their water balance under drought conditions.
Journal ArticleDOI
Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis.
Russel J. Reiter,Sergio Rosales-Corral,Dun Xian Tan,Darío Acuña-Castroviejo,Lilan Qin,Shun-Fa Yang,Kexin Xu +6 more
TL;DR: The experimental findings suggest that the advantages of using melatonin as a co-treatment with conventional cancer therapies would far exceed improvements in the wellbeing of the patients.
Journal ArticleDOI
The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo
Dun Xian Tan,Burkhard Poeggeler,Russel J. Reiter,Li Dun Chen,Shou Chen,Manchester C. Lucien,Lornell Barlow-Walden +6 more
TL;DR: The results suggest that melatonin protects against safrole associated DNA damage.