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Dun Xian Tan

Researcher at University of Texas Health Science Center at San Antonio

Publications -  315
Citations -  47893

Dun Xian Tan is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Melatonin & Oxidative stress. The author has an hindex of 117, co-authored 308 publications receiving 42258 citations. Previous affiliations of Dun Xian Tan include University of Texas System & University of Texas at Austin.

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Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions.

TL;DR: C3HOM is found to be a more potent antioxidant than melatonin or vitamin C in terms of its ability to scavenge the hydroxyl radical (HO.) and to recover oxidized horseradish peroxidase to its ground state.
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Role of melatonin in the epigenetic regulation of breast cancer

TL;DR: The oncostatic properties of melatonin as they directly or indirectly involve epigenetic mechanisms of cancer are reviewed with a special focus on breast cancer.
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Melatonin reduces lipid peroxidation and tissue edema in cerulein-induced acute pancreatitis in rats.

TL;DR: Melatonin's protective effects in cerulein-treated rats presumably relate to its radical scavenging ability and to other antioxidative processes induced bymelatonin.
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Beneficial actions of melatonin in the management of viral infections: a new use for this "molecular handyman"?

TL;DR: Clinical trials have shown that melatonin is efficient in preventing cell damage under acute and chronic states, and its properties as a potent antioxidant and antioxidant enzyme inducer, a regulator of apoptosis and a stimulator of immune functions support the use of melatonin in viral infections.
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Essential actions of melatonin in protecting the ovary from oxidative damage.

TL;DR: The functional role of reactive species and the cytoprotective properties of melatonin on the ovary from oxidative damage are summarized in this brief review.