E
E. Rand Sutherland
Researcher at University of Colorado Denver
Publications - 73
Citations - 10638
E. Rand Sutherland is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Asthma & COPD. The author has an hindex of 43, co-authored 73 publications receiving 9571 citations. Previous affiliations of E. Rand Sutherland include Anschutz Medical Campus & University of Colorado Boulder.
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Journal ArticleDOI
Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies.
TL;DR: Overweight and obesity are associated with a dose-dependent increase in the odds of incident asthma in men and women, suggesting asthma incidence could be reduced by interventions targeting overweight and obesity.
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Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
Sally E. Wenzel,Mario Castro,Jonathan Corren,Jorge Maspero,Lin Wang,Bingzhi Zhang,Gianluca Pirozzi,E. Rand Sutherland,Robert Evans,Vijay N. Joish,Laurent Eckert,Neil M.H. Graham,Neil Stahl,George D. Yancopoulos,Mariana Louis-Tisserand,Ariel Teper +15 more
TL;DR: This clinical trial aimed to assess the efficacy and safety of dupilumab as add-on therapy in patients with uncontrolled persistent asthma on medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist, irrespective of baseline eosinophil count.
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Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma.
Yvonne J. Huang,Craig E. Nelson,Eoin L. Brodie,Todd Z. DeSantis,Marshall S. Baek,Jane Liu,Tanja Woyke,Martin Allgaier,James Bristow,Jeanine P. Wiener-Kronish,E. Rand Sutherland,Tonya S. King,Nikolina Icitovic,Richard J. Martin,William J. Calhoun,Mario Castro,Loren C. Denlinger,Emily DiMango,Monica Kraft,Stephen P. Peters,Stephen I. Wasserman,Michael E. Wechsler,Homer A. Boushey,Susan V. Lynch +23 more
TL;DR: The composition of Bronchial airway microbiota is associated with the degree of bronchial hyperresponsiveness among patients with suboptimally controlled asthma, and these findings support the need for further functional studies to examine the potential contribution of members of theAirway microbiota in asthma pathogenesis.
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Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial
Claus Bachert,Claus Bachert,Leda Mannent,Robert M. Naclerio,Joaquim Mullol,Berrylin J. Ferguson,Philippe Gevaert,Peter Hellings,Lixia Jiao,Ling Wang,Robert Evans,Gianluca Pirozzi,Neil M.H. Graham,Brian N. Swanson,Jennifer D. Hamilton,Allen Radin,Namita Gandhi,Neil Stahl,George D. Yancopoulos,E. Rand Sutherland +19 more
TL;DR: Among adults with symptomatic chronic sinusitis and nasal polyposis refractory to intranasal corticosteroids, the addition of subcutaneous dupilumab to mometasone furoate nasal spray compared with mometAsone alone reduced endoscopic nasal polyp burden after 16 weeks.
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Management of chronic obstructive pulmonary disease.
TL;DR: This Monograph is an update that gives a comprehensive overview of most aspects of this serious disease and shows other treatment modalities have been shown to be successful.