E
E. Wolff
Researcher at University of Utah
Publications - 6
Citations - 3780
E. Wolff is an academic researcher from University of Utah. The author has contributed to research in topics: Gene & Chromosome 16. The author has an hindex of 5, co-authored 6 publications receiving 3726 citations. Previous affiliations of E. Wolff include Howard Hughes Medical Institute.
Papers
More filters
Journal ArticleDOI
Identification and characterization of the familial adenomatous polyposis coli gene
Joanna Groden,Andrew Thliveris,Andrew Thliveris,Wade S. Samowitz,M. Carlson,Lawrence Gelbert,Lawrence Gelbert,Hans Albertsen,Geoff Joslyn,Geoff Joslyn,Jeff Stevens,Jeff Stevens,Lisa Spirio,Margaret Robertson,Margaret Robertson,Leslie Sargeant,Leslie Sargeant,Karen Krapcho,Karen Krapcho,E. Wolff,E. Wolff,Randall W. Burt,John P. Hughes,Janet A. Warrington,John Douglas Mcpherson,John J. Wasmuth,Denis Le Paslier,Hadi Abderrahim,Daniel Cohen,Mark Leppert,Mark Leppert,Ray White,Ray White +32 more
TL;DR: DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes located within a 100 kb region deleted in two of the patients, and data have established that DP2.5 is the APC gene.
Journal ArticleDOI
Identification of deletion mutations and three new genes at the familial polyposis locus
Geoff Joslyn,Geoff Joslyn,M. Carlson,Andrew Thliveris,Andrew Thliveris,Hans Albertsen,Lawrence Gelbert,Lawrence Gelbert,Wade S. Samowitz,Joanna Groden,Jeff Stevens,Jeff Stevens,Lisa Spirio,Margaret Robertson,Margaret Robertson,Leslie Sargeant,Leslie Sargeant,Karen Krapcho,Karen Krapcho,E. Wolff,E. Wolff,Randall W. Burt,John P. Hughes,Janet A. Warrington,John Douglas Mcpherson,John J. Wasmuth,Denis Le Paslier,Hadi Abderrahim,Daniel Cohen,Mark Leppert,Mark Leppert,Ray White,Ray White +32 more
TL;DR: Small (100-260 kb), nested deletions were characterized in DNA from two unrelated patients with familial adenomatous polyposis coli (APC) and two new genes contained sequence identical to SRP19, the gene coding for the 19 kd component of the ribosomal signal recognition particle.
Journal Article
Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5.
Yusuke Nakamura,Mark Lathrop,Mark Leppert,M. Dobbs,Wasmuth J,E. Wolff,M. Carlson,Fujimoto E,Karen Krapcho,Sears T +9 more
TL;DR: Six additional polymorphic DNA markers in the near vicinity of the FAP locus represent a further step toward isolation of the genetic defect and provides the opportunity for preclinical diagnosis of risk status for colon cancer among individuals in families that are segregating adenomatous polyposis.
Journal Article
Fine structure DNA mapping studies of the chromosomal region harboring the genetic defect in neurofibromatosis type 1
Peter O'Connell,Robin J. Leach,D. H. Ledbetter,Richard M. Cawthon,Melanie Culver,J. R. Eldridge,A. K. Frej,T. Holm,E. Wolff,M. J. Thayer,Alan J. Schafer,J. W. Fountain,Margaret R. Wallace,F. S. Collins,Mark H. Skolnick,D. C. Rich,R. E. K. Fournier,Bonnie J. Baty,John C. Carey +18 more
TL;DR: The cosmids in the NF1 region will be an important resource for testing DNA blots of large-fragment restriction-enzyme digests from NF1 patient cell lines, to detect rearrangements in patients' DNA and to identify the 17;22 NF1 translocation breakpoint.