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Andrew Thliveris
Researcher at University of Utah
Publications - 10
Citations - 4543
Andrew Thliveris is an academic researcher from University of Utah. The author has contributed to research in topics: Adenomatous polyposis coli & Gene. The author has an hindex of 7, co-authored 10 publications receiving 4475 citations. Previous affiliations of Andrew Thliveris include Howard Hughes Medical Institute.
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Journal ArticleDOI
Identification and characterization of the familial adenomatous polyposis coli gene
Joanna Groden,Andrew Thliveris,Andrew Thliveris,Wade S. Samowitz,M. Carlson,Lawrence Gelbert,Lawrence Gelbert,Hans Albertsen,Geoff Joslyn,Geoff Joslyn,Jeff Stevens,Jeff Stevens,Lisa Spirio,Margaret Robertson,Margaret Robertson,Leslie Sargeant,Leslie Sargeant,Karen Krapcho,Karen Krapcho,E. Wolff,E. Wolff,Randall W. Burt,John P. Hughes,Janet A. Warrington,John Douglas Mcpherson,John J. Wasmuth,Denis Le Paslier,Hadi Abderrahim,Daniel Cohen,Mark Leppert,Mark Leppert,Ray White,Ray White +32 more
TL;DR: DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes located within a 100 kb region deleted in two of the patients, and data have established that DP2.5 is the APC gene.
Journal ArticleDOI
Identification of deletion mutations and three new genes at the familial polyposis locus
Geoff Joslyn,Geoff Joslyn,M. Carlson,Andrew Thliveris,Andrew Thliveris,Hans Albertsen,Lawrence Gelbert,Lawrence Gelbert,Wade S. Samowitz,Joanna Groden,Jeff Stevens,Jeff Stevens,Lisa Spirio,Margaret Robertson,Margaret Robertson,Leslie Sargeant,Leslie Sargeant,Karen Krapcho,Karen Krapcho,E. Wolff,E. Wolff,Randall W. Burt,John P. Hughes,Janet A. Warrington,John Douglas Mcpherson,John J. Wasmuth,Denis Le Paslier,Hadi Abderrahim,Daniel Cohen,Mark Leppert,Mark Leppert,Ray White,Ray White +32 more
TL;DR: Small (100-260 kb), nested deletions were characterized in DNA from two unrelated patients with familial adenomatous polyposis coli (APC) and two new genes contained sequence identical to SRP19, the gene coding for the 19 kd component of the ribosomal signal recognition particle.
Journal ArticleDOI
Alleles of the APC gene: An attenuated form of familial polyposis
Lisa Spirio,Sylviane Olschwang,Joanna Groden,Margaret Robertson,Wade S. Samowitz,Geoff Joslyn,Lawrence Gelbert,Andrew Thliveris,M. Carlson,Brith Otterud,Henry T. Lynch,Patrice Watson,Patrick M. Lynch,Pierre Laurent-Puig,Randall W. Burt,John P. Hughes,Gilles Thomas,Mark Leppert,Ray White +18 more
TL;DR: Four distinct mutations in the APC gene have now been identified in seven AAPC families, and they differ in that the four mutated sites are located very close to one another and nearer the 5' end of theAPC gene than any base substitutions or small deletions yet discovered in patients with classical APC.
Journal Article
Mutational analysis of patients with adenomatous polyposis : identical inactivating mutations in unrelated individuals
Joanna Groden,Lawrence Gelbert,Andrew Thliveris,Lesa Nelson,Margaret Robertson,Geoff Joslyn,Wade S. Samowitz,Lisa Spirio,M. Carlson,Randall W. Burt,Mark Leppert,Ray White +11 more
TL;DR: Samples of constitutional DNA from 60 unrelated patients with adenomatous polyposis coli (APC) were examined for mutations in the APC gene; five inactivating mutations were observed among 12 individuals with APC; all were different from the six inactivates reported in this panel of patients.
Journal Article
Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region
Lynn B. Jorde,W. S. Watkins,M. Carlson,Joanna Groden,Hans Albertsen,Andrew Thliveris,Mark Leppert +6 more
TL;DR: It is shown that linkage disequilibrium nearly always correlates significantly with physical distance in genomic regions > 50-60 kb but that it does not do so in smaller genomic regions.