J
Jeremy A. Guggenheim
Researcher at Cardiff University
Publications - 142
Citations - 5271
Jeremy A. Guggenheim is an academic researcher from Cardiff University. The author has contributed to research in topics: Population & Refractive error. The author has an hindex of 36, co-authored 131 publications receiving 3907 citations. Previous affiliations of Jeremy A. Guggenheim include Hong Kong Polytechnic University & University of Wales.
Papers
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Journal ArticleDOI
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
Virginie J. M. Verhoeven,Pirro G. Hysi,Robert Wojciechowski,Robert Wojciechowski,Qiao Fan,Jeremy A. Guggenheim,René Höhn,Stuart MacGregor,Alex W. Hewitt,Alex W. Hewitt,Abhishek Nag,Ching-Yu Cheng,Ching-Yu Cheng,Ekaterina Yonova-Doing,Xin Zhou,M. Kamran Ikram,M. Kamran Ikram,Gabriëlle H.S. Buitendijk,George McMahon,John P. Kemp,Beate St Pourcain,Claire L. Simpson,Kari-Matti Mäkelä,Terho Lehtimäki,Mika Kähönen,Andrew D. Paterson,S. Mohsen Hosseini,Hoi Suen Wong,Liang Xu,Jost B. Jonas,Olavi Pärssinen,Juho Wedenoja,Shea Ping Yip,Daniel W.H. Ho,Daniel W.H. Ho,Chi Pui Pang,Li Jia Chen,Kathryn P. Burdon,Jamie E Craig,Barbara E.K. Klein,Ronald Klein,Toomas Haller,Andres Metspalu,Chiea Chuen Khor,Chiea Chuen Khor,E-Shyong Tai,Tin Aung,Tin Aung,Eranga N. Vithana,Wan Ting Tay,Veluchamy A. Barathi,Veluchamy A. Barathi,Myopia (Cream),Peng Chen,Ruoying Li,Jiemin Liao,Yingfeng Zheng,Rick Twee-Hee Ong,Angela Döring,Complications Trial,Complications (Dcct),David M. Evans,Nicholas J. Timpson,Annemieke J.M.H. Verkerk,Thomas Meitinger,Olli T. Raitakari,Felicia Hawthorne,Tim D. Spector,Lennart C. Karssen,Mario Pirastu,Federico Murgia,Wei Ang,Aniket Mishra,Grant W. Montgomery,Craig E. Pennell,Phillippa M. Cumberland,Ioana Cotlarciuc,Paul Mitchell,Jie Jin Wang,Jie Jin Wang,Maria Schache,Sarayut Janmahasatian,Robert P. Igo,Jonathan H. Lass,Emily Y. Chew,Sudha K. Iyengar,Theo G. M. F. Gorgels,Igor Rudan,Caroline Hayward,Alan F. Wright,Ozren Polasek,Zoran Vatavuk,James F. Wilson,Brian W Fleck,Tanja Zeller,Alireza Mirshahi,Christian P. Müller,André G. Uitterlinden,Fernando Rivadeneira,Johannes R. Vingerling,Albert Hofman,Ben A. Oostra,Najaf Amin,Arthur A.B. Bergen,Yik Ying Teo,Jugnoo S Rahi,Jugnoo S Rahi,Jugnoo S Rahi,Veronique Vitart,Cathy Williams,Paul N. Baird,Tien Yin Wong,Tien Yin Wong,Konrad Oexle,Norbert Pfeiffer,David A. Mackey,David A. Mackey,Terri L. Young,Cornelia M. van Duijn,Seang-Mei Saw,Seang-Mei Saw,Seang-Mei Saw,Joan E. Bailey-Wilson,Joan E. Bailey-Wilson,Dwight Stambolian,Caroline C W Klaver,Caroline C W Klaver,Christopher J Hammond,Christopher J Hammond +128 more
TL;DR: The CREAM consortium conducted genome-wide meta-analyses, which identified 16 new loci for refractive error in individuals of European ancestry and 8 were shared with Asians, and identified 8 additional associated loci.
Journal ArticleDOI
Time outdoors and physical activity as predictors of incident myopia in childhood: A prospective cohort study
Jeremy A. Guggenheim,Kate Northstone,George McMahon,Andy R Ness,Kevin Deere,Callum Mattocks,Beate St Pourcain,Cathy Williams +7 more
TL;DR: Time spent outdoors was predictive of incident myopia independently of physical activity level, and the greater association observed for time outdoors suggests that the previously reported link between "sports/outdoor activity" and incidentMyopia is due mainly to its capture of information relating to time outdoors rather than physical activity.
Journal ArticleDOI
IMI - Interventions Myopia Institute: Interventions for Controlling Myopia Onset and Progression Report.
Christine F. Wildsoet,Audrey Chia,Pauline Cho,Jeremy A. Guggenheim,Jan Roelof Polling,Scott A. Read,Padmaja Sankaridurg,Seang-Mei Saw,Klaus Trier,Jeffrey J. Walline,Pei Chang Wu,James S. Wolffsohn +11 more
TL;DR: There are multiple avenues for intervention worthy of exploration in all categories, although in the case of optical, pharmacological, and behavioral interventions for preventing or slowing progression of myopia, treatment efficacy at an individual level appears quite variable.
Journal Article
Form-Deprivation Myopia Induces Activation of Scleral Matrix Metalloproteinase-2 in Tree Shrew
TL;DR: It is demonstrated that form-deprivation myopia and recovery from myopia alter scleral catabolism and provide further support for the theory that changes in eye size during mammalian refractive development are the result of active tissue remodeling rather than passive sCleral stretching alone.
Journal ArticleDOI
Education and myopia: assessing the direction of causality by mendelian randomisation
Edward Mountjoy,Neil M Davies,Denis Plotnikov,George Davey Smith,Santiago Rodriguez,Cathy Williams,Jeremy A. Guggenheim,Denize Atan +7 more
TL;DR: This study shows that exposure to more years in education contributes to the rising prevalence of myopia, and increasing the length of time spent in education may inadvertently increase the prevalence ofMyopia and potential future visual disability.