E
Edward R. Burns
Researcher at Albert Einstein College of Medicine
Publications - 47
Citations - 1768
Edward R. Burns is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Population & Anemia. The author has an hindex of 19, co-authored 47 publications receiving 1641 citations. Previous affiliations of Edward R. Burns include Montefiore Medical Center & Yeshiva University.
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Journal ArticleDOI
The history of African gene flow into Southern Europeans, Levantines, and Jews.
Priya Moorjani,Nick Patterson,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Alon Keinan,Li Hao,Gil Atzmon,Edward R. Burns,Harry Ostrer,Alkes L. Price,David Reich,David Reich +12 more
TL;DR: Genetic data is analyzed from about 40 West Eurasian groups to show that almost all Southern Europeans have inherited 1%–3% African ancestry with an average mixture date of around 55 generations ago, consistent with North African gene flow at the end of the Roman Empire and subsequent Arab migrations.
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Abraham's Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry
Gil Atzmon,Li Hao,Itsik Pe'er,Christopher Velez,Alexander Pearlman,Pier Francesco Palamara,Bernice E. Morrow,Eitan Friedman,Carole Oddoux,Edward R. Burns,Harry Ostrer +10 more
TL;DR: This study demonstrates that European/Syrian and Middle Eastern Jews represent a series of geographical isolates or clusters woven together by shared IBD genetic threads.
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Gene flow from North Africa contributes to differential human genetic diversity in southern Europe
Laura R. Botigué,Brenna M. Henn,Simon Gravel,Brian K. Maples,Christopher R. Gignoux,Erik Corona,Erik Corona,Gil Atzmon,Edward R. Burns,Harry Ostrer,Carlos Flores,Jaume Bertranpetit,David Comas,Carlos Bustamante +13 more
TL;DR: The source of genetic diversity in southern Europe has important biomedical implications and it is found that most disease risk alleles from genome-wide association studies follow expected patterns of divergence between Europe and North Africa, with the principal exception of multiple sclerosis.
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A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci
Eimear E. Kenny,Itsik Pe'er,Amir Karban,Laurie J. Ozelius,Adele A. Mitchell,Sok Meng Evelyn Ng,Monica Erazo,Harry Ostrer,Clara Abraham,Maria T. Abreu,Gil Atzmon,Nir Barzilai,Steven R. Brant,Susan B. Bressman,Edward R. Burns,Yehuda Chowers,Lorraine N. Clark,Ariel Darvasi,Dana Doheny,Richard H. Duerr,Rami Eliakim,Nir Giladi,Peter K. Gregersen,Hakon Hakonarson,Matthew Jones,Karen Marder,Dermot P.B. McGovern,Jennifer G. Mulle,Avi Orr-Urtreger,Deborah D. Proctor,Ann E. Pulver,Jerome I. Rotter,Mark S. Silverberg,Thomas A. Ullman,Stephen T. Warren,Matti Waterman,Wei Zhang,Aviv Bergman,Lloyd Mayer,Seymour Katz,Robert J. Desnick,Judy H. Cho,Inga Peter +42 more
TL;DR: This study confirmed genome-wide significant associations of 9 known CD loci in AJs and replicated 3 additional loci with strong signal and discovered 16 replicated and newly discovered loci, which accounted for 11.2% of the total genetic variance for CD risk in the AJ population.
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Morphologic diagnosis of thrombotic thrombocytopenic purpura.
TL;DR: An initial schistocyte count of greater than 1% strongly suggests a diagnosis of TTP in the absence of other known causes of thrombotic microangiopathy.