P
Priya Moorjani
Researcher at University of California, Berkeley
Publications - 55
Citations - 8741
Priya Moorjani is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Population & Germline mutation. The author has an hindex of 28, co-authored 48 publications receiving 7160 citations. Previous affiliations of Priya Moorjani include Harvard University & George Washington University.
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Journal ArticleDOI
Ancient Admixture in Human History
Nick Patterson,Priya Moorjani,Yontao Luo,Swapan Mallick,Nadin Rohland,Yiping Zhan,Teri Genschoreck,Teresa Webster,David Reich,David Reich +9 more
TL;DR: A suite of methods for learning about population mixtures are presented, implemented in a software package called ADMIXTOOLS, that support formal tests for whether mixture occurred and make it possible to infer proportions and dates of mixture.
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The complete genome sequence of a Neanderthal from the Altai Mountains
Kay Prüfer,Fernando Racimo,Nick Patterson,Flora Jay,Sriram Sankararaman,Susanna Sawyer,Anja Heinze,Gabriel Renaud,Peter H. Sudmant,Cesare de Filippo,Heng Li,Swapan Mallick,Michael Dannemann,Qiaomei Fu,Martin Kircher,Martin Kuhlwilm,Michael Lachmann,Matthias Meyer,Matthias Ongyerth,Michael Siebauer,Christoph Theunert,Arti Tandon,Priya Moorjani,Joseph K. Pickrell,James C. Mullikin,Samuel H. Vohr,Richard E. Green,Ines Hellmann,Philip L. F. Johnson,Hélène Blanché,Howard M. Cann,Jacob O. Kitzman,Jay Shendure,Evan E. Eichler,Ed S. Lein,Trygve E. Bakken,Liubov V. Golovanova,Vladimir B. Doronichev,Michael V. Shunkov,A.P. Derevianko,Bence Viola,Montgomery Slatkin,David Reich,Janet Kelso,Svante Pääbo +44 more
TL;DR: It is shown that interbreeding, albeit of low magnitude, occurred among many hominin groups in the Late Pleistocene and a definitive list of substitutions that became fixed in modern humans after their separation from the ancestors of Neanderthals and Denisovans is established.
Journal ArticleDOI
Genome sequence of a 45,000-year-old modern human from western Siberia
Qiaomei Fu,Heng Li,Priya Moorjani,Flora Jay,Sergey Mikhailovich Slepchenko,Aleksei A. Bondarev,Philip L. F. Johnson,Ayinuer Aximu-Petri,Kay Prüfer,Cesare de Filippo,Matthias Meyer,Nicolas Zwyns,Domingo C. Salazar-García,Yaroslav V. Kuzmin,Susan G. Keates,Pavel A. Kosintsev,Dmitry Razhev,Michael P. Richards,Nikolai V. Peristov,Michael Lachmann,Katerina Douka,Thomas Higham,Montgomery Slatkin,Jean-Jacques Hublin,David Reich,Janet Kelso,T. Bence Viola,Svante Pääbo +27 more
TL;DR: The high-quality genome sequence of a ∼45,000-year-old modern human male from Siberia derives from a population that lived before—or simultaneously with—the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians.
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Complete Khoisan and Bantu genomes from southern Africa
Stephan C. Schuster,Webb Miller,Aakrosh Ratan,Lynn P. Tomsho,Belinda Giardine,Lindsay R. Kasson,Robert S. Harris,Desiree C. Petersen,Fangqing Zhao,Ji Qi,Can Alkan,Jeffrey M. Kidd,Yazhou Sun,Daniela I. Drautz,Pascal Bouffard,Donna M. Muzny,Jeffrey G. Reid,Lynne V. Nazareth,Qingyu Wang,Richard Burhans,Cathy Riemer,Nicola E. Wittekindt,Priya Moorjani,Elizabeth A. Tindall,Charles G. Danko,Wee Siang Teo,Anne M. Buboltz,Zhenhai Zhang,Qianyi Ma,Arno Oosthuysen,Abraham W. Steenkamp,Hermann Oostuisen,Philippus Venter,John P. Gajewski,Yu Zhang,B. Franklin Pugh,Kateryna D. Makova,Anton Nekrutenko,Elaine R. Mardis,Nick Patterson,Tom H. Pringle,Francesca Chiaromonte,James C. Mullikin,Evan E. Eichler,Ross C. Hardison,Richard A. Gibbs,Timothy T. Harkins,Vanessa M. Hayes +47 more
TL;DR: The extent of whole-genome and exome diversity among the five men, reporting 1.3 million novel DNA differences genome-wide, including 13,146 novel amino acid variants, suggests the Bushmen seem to be more different from each other than, for example, a European and an Asian.
Journal ArticleDOI
Inferring Admixture Histories of Human Populations Using Linkage Disequilibrium
Po-Ru Loh,Mark Lipson,Nick Patterson,Priya Moorjani,Priya Moorjani,Joseph K. Pickrell,David Reich,David Reich,Bonnie Berger,Bonnie Berger +9 more
TL;DR: In this paper, a new approach harnesses the exponential decay of admixture-induced linkage disequilibrium (LD) as a function of genetic distance, which can be used to infer mixture proportions as well as dates with fewer constraints on reference populations.