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Amir Karban
Researcher at Rambam Health Care Campus
Publications - 78
Citations - 8500
Amir Karban is an academic researcher from Rambam Health Care Campus. The author has contributed to research in topics: Inflammatory bowel disease & Population. The author has an hindex of 26, co-authored 78 publications receiving 7750 citations. Previous affiliations of Amir Karban include Johns Hopkins University & Rappaport Faculty of Medicine.
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Journal ArticleDOI
Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more
TL;DR: The introduction of a widely acceptable clinical subclassification is strongly advocated, which would allow detailed correlations among serotype, genotype and clinical phenotype to be examined and confirmed in independent cohorts of patients and, thereby, provide a vital foundation for future work.
Journal ArticleDOI
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke,Dermot P.B. McGovern,Jeffrey C. Barrett,Kai Wang,Graham L. Radford-Smith,Tariq Ahmad,Charlie W. Lees,Tobias Balschun,James Lee,Rebecca L. Roberts,Carl A. Anderson,Joshua C. Bis,Suzanne Bumpstead,David Ellinghaus,Eleonora M. Festen,Michel Georges,Todd Green,Talin Haritunians,Luke Jostins,Anna Latiano,Christopher G. Mathew,Grant W. Montgomery,Natalie J. Prescott,Soumya Raychaudhuri,Jerome I. Rotter,Philip Schumm,Yashoda Sharma,Lisa A. Simms,Kent D. Taylor,David C. Whiteman,Cisca Wijmenga,Robert N. Baldassano,Murray L. Barclay,Theodore M. Bayless,Stephan Brand,Carsten Büning,Albert Cohen,Jean Frederick Colombel,Mario Cottone,Laura Stronati,Ted Denson,Martine De Vos,Renata D'Incà,Marla Dubinsky,Cathryn Edwards,Timothy H. Florin,Denis Franchimont,Richard B. Gearry,Jürgen Glas,Jürgen Glas,Jürgen Glas,André Van Gossum,Stephen L. Guthery,Jonas Halfvarson,Hein W. Verspaget,Jean-Pierre Hugot,Amir Karban,Debby Laukens,Ian C. Lawrance,Marc Lémann,Arie Levine,Cécile Libioulle,Edouard Louis,Craig Mowat,William G. Newman,Julián Panés,Anne M. Phillips,Deborah D. Proctor,Miguel Regueiro,Richard K Russell,Paul Rutgeerts,Jeremy D. Sanderson,Miquel Sans,Frank Seibold,A. Hillary Steinhart,Pieter C. F. Stokkers,Leif Törkvist,Gerd A. Kullak-Ublick,David C. Wilson,Thomas D. Walters,Stephan R. Targan,Steven R. Brant,John D. Rioux,Mauro D'Amato,Rinse K. Weersma,Subra Kugathasan,Anne M. Griffiths,John C. Mansfield,Severine Vermeire,Richard H. Duerr,Mark S. Silverberg,Jack Satsangi,Stefan Schreiber,Judy H. Cho,Vito Annese,Hakon Hakonarson,Mark J. Daly,Miles Parkes +97 more
TL;DR: A meta-analysis of six Crohn's disease genome-wide association studies and a series of in silico analyses highlighted particular genes within these loci implicated functionally interesting candidate genes including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2 and TAGAP.
Journal ArticleDOI
Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules
Morad Nakhleh,Haitham Amal,Raneen Jeries,Yoav Y. Broza,Manal Aboud,A'laa Gharra,Hodaya Ivgi,Salam Khatib,Shifaa' Badarneh,Lior Har-Shai,Lea Glass-Marmor,Izabella Lejbkowicz,Ariel Miller,Samih Badarny,Raz Winer,John P.M. Finberg,Sylvia Cohen-Kaminsky,Frédéric Perros,David Montani,Barbara Girerd,Gilles Garcia,Gérald Simonneau,Farid Nakhoul,Shira Baram,Raed Salim,Marwan Hakim,Maayan Gruber,Ohad Ronen,Tal Marshak,Ilana Doweck,Ofer Nativ,Zaher Bahouth,Da-you Shi,Wei Zhang,Qing-Ling Hua,Yue-Yin Pan,Li Tao,Hu Liu,Amir Karban,Eduard Koifman,Tova Rainis,Roberts Skapars,Armands Sivins,Guntis Ancans,Inta Liepniece-Karele,Ilze Kikuste,Ieva Lasina,Ivars Tolmanis,Douglas W. Johnson,Stuart Z. Millstone,Jennifer Fulton,John W. Wells,Larry H. Wilf,Marc Humbert,Marcis Leja,Nir Peled,Hossam Haick +56 more
TL;DR: An artificially intelligent nanoarray based on molecularly modified gold nanoparticles and a random network of single-walled carbon nanotubes for noninvasive diagnosis and classification of a number of diseases from exhaled breath could contribute to one of the most important criteria for successful health intervention in the modern era.
Journal ArticleDOI
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis
Amir Karban,Toshihiko Okazaki,Carolien I.M. Panhuysen,Thomas Gallegos,James J. Potter,Joan E. Bailey-Wilson,Mark S. Silverberg,Richard H. Duerr,Judy H. Cho,Peter K. Gregersen,Yuqiong Wu,Jean Paul Achkar,Themistocles Dassopoulos,Esteban Mezey,Theodore M. Bayless,Franklin J. Nouvet,Steven R. Brant +16 more
TL;DR: The first potentially functional polymorphism of NFKB1 is identified and its genetic association with a common human disease, ulcerative colitis is demonstrated.
Journal ArticleDOI
MDR1 Ala893 Polymorphism Is Associated with Inflammatory Bowel Disease
Steven R. Brant,Steven R. Brant,Carolien I.M. Panhuysen,Dan L. Nicolae,Deepthi M. Reddy,Denise K. Bonen,Reda Karaliukas,Leilei Zhang,Eric Swanson,Lisa W. Datta,Thomas M. Moran,Geoffrey Ravenhill,Richard H. Duerr,Jean Paul Achkar,Amir Karban,Judy H. Cho +15 more
TL;DR: The association of the common Ala893 polymorphism with IBD specifically and with the murine model of mdr1 deficiency provides additional support for its contribution to interindividual pharmacogenetic variation.