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Eitan Friedman

Researcher at Sheba Medical Center

Publications -  516
Citations -  24345

Eitan Friedman is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Breast cancer & Population. The author has an hindex of 77, co-authored 487 publications receiving 21871 citations. Previous affiliations of Eitan Friedman include Tel Aviv University & City University of New York.

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Journal ArticleDOI

Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women With a BRCA1 or BRCA2 Mutation

Amy Finch, +25 more
- 12 Jul 2006 - 
TL;DR: Oophorectomy is associated with reduced risk of ovarian and fallopian tube cancer in high-risk women, although there is a substantial residual risk for peritoneal cancer in BRCA1 and BRCa2 mutation carriers following prophylactic salpingo-oophoreCTomy.
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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Stig E. Bojesen, +455 more
- 01 Apr 2013 - 
TL;DR: Using the Illumina custom genotyping array iCOGs, SNPs at the TERT locus in breast, ovarian and BRCA1 mutation carrier cancer cases and controls and leukocyte telomere measurements are analyzed to find associations cluster into three independent peaks.
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Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study

Andrea Eisen, +19 more
- 20 Oct 2005 - 
TL;DR: Oophorectomy is an effective means of reducing the risk of breast cancer in carriers of BRCA1 mutations, and the data suggest oophoreCTomy is protective in BRCa2 carriers as well, but needs to be confirmed in other studies.
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An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Catherine A. Brownstein, +210 more
- 25 Mar 2014 - 
TL;DR: The CLARITY Challenge provides a comprehensive assessment of current practices for using genome sequencing to diagnose and report genetic diseases and reveals a general convergence of practices on most elements of the analysis and interpretation process.
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Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

Fergus J. Couch, +261 more
- 27 Mar 2013 - 
TL;DR: It is estimated that the breast cancer lifetime risks for the5% of BRCA1 carriers at lowest risk are 28%–50% compared to 81%–100% for the 5% at highest risk, and the ovarian cancer lifetime risk is 63% or higher, based on the known cancer risk-modifying loci.