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Edwin H. Cook
Researcher at University of Illinois at Chicago
Publications - 339
Citations - 61045
Edwin H. Cook is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Autism & Heritability of autism. The author has an hindex of 102, co-authored 337 publications receiving 54518 citations. Previous affiliations of Edwin H. Cook include University of Chicago & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Parental Broader Autism Subphenotypes in ASD Affected Families: Relationship to Gender, Child's Symptoms, SSRI Treatment, and Platelet Serotonin
Tal Levin-Decanini,Nell Maltman,Sunday M. Francis,Steve Guter,George M. Anderson,Edwin H. Cook,Suma Jacob +6 more
TL;DR: Study results suggest that the expression of the BAP varies not only across parental gender, but also across individuals using psychotropic medication and those who do not, and significant parent–child correlations were observed for 5HT levels.
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Mitochondrial small RNAs that are up-regulated in hippocampus during olfactory discrimination training in mice.
TL;DR: Small RNAs may link behavioral plasticity to protein synthesis and replication of mitochondria to support dendritic growth, spine stabilization, and synapse formation in mice trained to execute a nose-poke.
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Platelet 5-HT2 serotonin receptor binding sites in autistic children and their first-degree relatives
TL;DR: This article examined platelet serotonin2 receptor binding sites, whole blood serotonin (5-HT), and plasma norepinephrine (NE) in male autistic children and their first-degree relatives.
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Variants in the α2A AR adrenergic receptor gene in psychiatric patients
Jinong Feng,Janet L. Sobell,Leonard L. Heston,David Goldman,Edwin H. Cook,Henry R. Kranzler,Joel Gelernter,Steve S. Sommer +7 more
TL;DR: Four missense changes found in patients with schizophrenia, attention deficit hyperactivity disorder, autism, alcohol dependence, or cocaine dependence occur in highly conserved amino acids, suggesting that these are of likely functional significance.
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Familiality of behavioral flexibility and response inhibition deficits in autism spectrum disorder (ASD)
Lauren M. Schmitt,Lauren M. Schmitt,Erin K. Bojanek,Stormi P. White,Michael E. Ragozzino,Edwin H. Cook,John A. Sweeney,Matthew W. Mosconi +7 more
TL;DR: Evidence is provided that behavioral flexibility and response inhibition impairments track differentially with ASD risk mechanisms and related behavioral traits, suggesting they co-segregate in families with parental subclinical social, communication and rigid personality traits.