E
Elluri Seetharami Reddy
Researcher at Emory University
Publications - 14
Citations - 187
Elluri Seetharami Reddy is an academic researcher from Emory University. The author has contributed to research in topics: Antibody & Medicine. The author has an hindex of 4, co-authored 8 publications receiving 95 citations. Previous affiliations of Elluri Seetharami Reddy include Indian Institutes of Technology.
Papers
More filters
Journal ArticleDOI
Characterization of human CD8 T cell responses in dengue virus infected patients from India
Anmol Chandele,Jaturong Sewatanon,Jaturong Sewatanon,Sivaram Gunisetty,Mohit Singla,Nattawat Onlamoon,Rama Akondy,Haydn T. Kissick,Kaustuv Nayak,Elluri Seetharami Reddy,Haroon Kalam,Dhiraj Kumar,Anil Verma,Harekrushna Panda,Siyu Wang,Nasikarn Angkasekwinai,Kovit Pattanapanyasat,Kulkanya Chokephaibulkit,Guruprasad R. Medigeshi,Rakesh Lodha,Sushil K. Kabra,Rafi Ahmed,Kaja Murali-Krishna +22 more
TL;DR: CD8 T cell subsets in dengue patients from India and Thailand are comprehensively characterized and it is revealed that these cells expand massively and express phenotypes indicative of overwhelming antigenic stimulus and tissue homing/cytotoxic-effector functions but that the vast majority of them fail to produce IFN-γ in vitro.
Journal ArticleDOI
An HIV-1 Broadly Neutralizing Antibody from a Clade C-Infected Pediatric Elite Neutralizer Potently Neutralizes the Contemporaneous and Autologous Evolving Viruses
Sanjeev Kumar,Harekrushna Panda,Muzamil Ashraf Makhdoomi,Nitesh Mishra,Haaris Ahsan Safdari,Himanshi Chawla,Heena Aggarwal,Elluri Seetharami Reddy,Rakesh Lodha,Sushil K. Kabra,Anmol Chandele,Somnath Dutta,Kalpana Luthra +12 more
TL;DR: Evaluated the specificity of plasma neutralizing antibodies of an antiretroviral-naive HIV-1 clade C chronically infected pediatric elite neutralizer, AIIMS_330, and found that plasma antibodies showed broad and potent HIV- 1 neutralizing activity with >87% breadth, a median inhibitory dilution (ID50) value of 1,246, and presence of N160 and N332 supersite-dependent HIV-2 bNAbs.
Journal ArticleDOI
Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India.
Kaustuv Nayak,Kamalvishnu P. Gottimukkala,Sanjeev Kumar,Elluri Seetharami Reddy,Venkata Viswanadh Edara,Robert C. Kauffman,Katharine Floyd,Grace Mantus,Deepali Savargaonkar,Pawan Kumar Goel,Satyam Arora,Manju Rahi,Carl W. Davis,Susanne L. Linderman,Jens Wrammert,Mehul S. Suthar,Rafi Ahmed,Amit Sharma,Kaja Murali-Krishna,Anmol Chandele +19 more
TL;DR: In this paper, the authors examined SARS-CoV-2 neutralizing antibodies, IgG, IgM, IgA and memory B cells in COVID-19 recovered individual from India.
Journal ArticleDOI
Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody
Sanjeev Kumar,Anamika Patel,Lilin Lai,Chennareddy Chakravarthy,Rajesh M. Valanparambil,Elluri Seetharami Reddy,Kamalvishnu P. Gottimukkala,Meredith E. Davis-Gardner,Venkata Viswanadh Edara,Susanne L. Linderman,Kaustuv Nayak,Kritika Dixit,Pragati Sharma,Prashant Kumar Bajpai,Vanshika Singh,Filipp Frank,Narayanaiah Cheedarla,Hans Verkerke,Andrew S. Neish,John D. Roback,Grace Mantus,Pawan Goel,Manju Rahi,Carl W. Davis,Jens Wrammert,Sucheta Godbole,Amy R. Henry,Daniel C. Douek,Mehul S. Suthar,Rafi Ahmed,Eric A. Ortlund,Amit Sharma,Kaja Murali-Krishna,Anmol Chandele +33 more
TL;DR: A receptor binding domain (RBD)–specific mAb 002-S21F2 that has rare gene usage and potently neutralized live viral isolates of SARS-CoV-2 variants including Omicron sublineages is found by characterizing several human monoclonal antibodies isolated from single B cells of the COVID-19–recovered individuals in India.
Posted ContentDOI
Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India
Kaustuv Nayak,Kamalvishnu P. Gottimukkala,Sanjeev Kumar,Elluri Seetharami Reddy,Elluri Seetharami Reddy,Venkata Viswanadh Edara,Venkata Viswanadh Edara,Robert C. Kauffman,Katharine Floyd,Katharine Floyd,Grace Mantus,Deepali Savargaonkar,Pawan Kumar Goel,Satyam Arora,Manju Rahi,Carl W. Davis,Susanne L. Linderman,Jens Wrammert,Mehul S. Suthar,Mehul S. Suthar,Rafi Ahmed,Amit Sharma,Amit Sharma,Kaja Murali-Krishna,Anmol Chandele +24 more
TL;DR: It is highlighted that PCR-confirmed convalescent COVID-19 individuals develop SARS-CoV-2 RBD-specific IgG antibodies, which correlate strongly with theirneutralizing antibody titers, which can serve as a valuable surrogate measurement for neutralizing antibody responses.