E
Erwin Neher
Researcher at Max Planck Society
Publications - 208
Citations - 54453
Erwin Neher is an academic researcher from Max Planck Society. The author has contributed to research in topics: Exocytosis & Calyx of Held. The author has an hindex of 107, co-authored 200 publications receiving 53036 citations. Previous affiliations of Erwin Neher include University of Giessen & Macau University of Science and Technology.
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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.
TL;DR: The extracellular patch clamp method, which first allowed the detection of single channel currents in biological membranes, has been further refined to enable higher current resolution, direct membrane patch potential control, and physical isolation of membrane patches.
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Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release.
TL;DR: The results obtained allowed us to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds.
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Sodium and calcium channels in bovine chromaffin cells
TL;DR: Inward currents in chromaffin cells were studied with the patch‐clamp technique and current recordings were obtained in cell‐attached, outside‐out and whole‐cell recording configurations.
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Multiple roles of calcium ions in the regulation of neurotransmitter release.
Erwin Neher,Takeshi Sakaba +1 more
TL;DR: Two distinct roles of [Ca(2+)] are proposed in vesicle recruitment: one accelerating "molecular priming" (vesicle docking and the buildup of a release machinery), the other promoting the tight coupling between releasable vesicles and Ca(2+) channels.
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Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells
TL;DR: In this article, the authors show that under voltage-clamp conditions, stochastically occurring signals can be recorded from adrenal chromaffin cells using a carbon-fibre electrode as an electrochemical detector.