E
Esper G. Kallas
Researcher at University of São Paulo
Publications - 291
Citations - 15157
Esper G. Kallas is an academic researcher from University of São Paulo. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 51, co-authored 255 publications receiving 12763 citations. Previous affiliations of Esper G. Kallas include University of Rochester & Global Virus Network.
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Journal ArticleDOI
Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
Robert M. Grant,Javier R. Lama,Peter L. Anderson,Vanessa McMahan,Albert Y. Liu,Lorena Vargas,Pedro Goicochea,Martin Casapia,Juan Vicente Guanira-Carranza,Maria Esther Ramirez-Cardich,Orlando Montoya-Herrera,Telmo Fernandez,Valdilea G. Veloso,Susan Buchbinder,Suwat Chariyalertsak,Mauro Schechter,Linda-Gail Bekker,Kenneth H. Mayer,Esper G. Kallas,K. Rivet Amico,Kathleen Mulligan,Lane R. Bushman,Robert J. Hance,Carmela Ganoza,Patricia Defechereux,Brian S. Postle,Furong Wang,J. Jeff McConnell,Jia-Hua Zheng,Jeanny Lee,James F. Rooney,Howard S. Jaffe,Ana Martinez,David N. Burns,David V. Glidden +34 more
TL;DR: Oral FTC-TDF provided protection against the acquisition of HIV infection among the subjects and Detectable blood levels strongly correlated with the prophylactic effect.
Journal ArticleDOI
Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study
Robert M. Grant,Robert M. Grant,Robert M. Grant,Peter L. Anderson,Vanessa McMahan,Albert Y. Liu,K. Rivet Amico,Megha Mehrotra,Sybil G. Hosek,Carlos Mosquera,Martin Casapia,Orlando Montoya,Susan Buchbinder,Valdilea G. Veloso,Kenneth H. Mayer,Suwat Chariyalertsak,Linda-Gail Bekker,Esper G. Kallas,Mauro Schechter,Juan V. Guanira,Lane R. Bushman,David N. Burns,James F. Rooney,David V. Glidden +23 more
TL;DR: The effect of PrEP is increased by greater uptake and adherence during periods of higher risk, and drug concentrations in dried blood spots are strongly correlated with protective benefit.
Journal ArticleDOI
Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men.
Peter L. Anderson,David V. Glidden,Albert Y. Liu,Susan Buchbinder,Javier R. Lama,Juan V. Guanira,Vanessa McMahan,Lane R. Bushman,Martin Casapia,Orlando Montoya-Herrera,Valdilea G. Veloso,Kenneth H. Mayer,Kenneth H. Mayer,Suwat Chariyalertsak,Mauro Schechter,Linda-Gail Bekker,Esper G. Kallas,Robert M. Grant +17 more
TL;DR: PrEP using oral FTC-TDF tablets is a robust intervention for preventing HIV acquisition among men who have sex with men, and specific drug concentrations associated with protection from HIV-1 acquisition in the iPrEx trial are estimated.
Journal ArticleDOI
Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans.
TL;DR: Although the SIV challenge model is incompletely validated, it is proposed that its expanded use can help facilitate the prioritization of candidate HIV-1 vaccines, ensuring that resources are focused on the most promising candidates.
Journal ArticleDOI
International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials
T. Christopher Mast,Lisa Kierstead,Swati B. Gupta,Alexander Nikas,Esper G. Kallas,Vladimir Novitsky,Bernard Mbewe,Punee Pitisuttithum,Mauro Schechter,Eftyhia Vardas,Nathan D. Wolfe,Miguel Aste-Amezaga,Danilo R. Casimiro,Paul Coplan,Walter L. Straus,John W. Shiver +15 more
TL;DR: Adenovirus NA titers varied by geographic location and were higher in non-US and non-European settings, especially Thailand, where participants from Thailand had the highest odds of having high Ad5 titers.