F
Fabrice Barlesi
Researcher at Aix-Marseille University
Publications - 666
Citations - 36214
Fabrice Barlesi is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 64, co-authored 582 publications receiving 25403 citations. Previous affiliations of Fabrice Barlesi include Institut Gustave Roussy & Nord University.
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Journal ArticleDOI
Comprehensive genome profiling in patients with metastatic non-small cell lung cancer: the precision medicine phase 2 randomized SAFIR02-Lung trial.
Fabrice Barlesi,Pascale Tomasini,Maryam Karimi,Stefan Michiels,Judith Raimbourg,Catherine Daniel,H. Janicot,A. Madroszyk,Clarisse Audigier-Valette,Elisabeth Quoix,Julien Mazieres,Denis Moro-Sibilot,Eric Dansin,Olivier Molinier,Hugues Morel,Eric Pichon,Alexis B. Cortot,Josiane Otto,F. Chomy,Pierre-Jean Souquet,Nicolas Cloarec,Etienne Giroux Leprieur,Ivan Bièche,Ludovic Lacroix,Sandrine Boyault,Valéry Attignon,Isabelle Soubeyran,Alain Morel,Alicia Tran-Dien,Alexandra Jacquet,Filippo Gustavo Dall'Olio,Marta Jimenez,Jean-Charles Soria,Benjamin Besse +33 more
TL;DR: Molecular profiling can feasibly be implemented to guide treatment choice for the maintenance strategy in EGFR/ALK wt NSCLC; in the current study it did not lead to substantial treatment benefits beyond durvalumab for PD-L1 ≥ 1 patients.
Journal ArticleDOI
Afatinib in combination with pembrolizumab in patients (pts) with stage IIIB/IV squamous cell carcinoma (SCC) of the lung.
Benjamin Levy,Luis Paz-Ares,Jaafar Bennouna,Enriqueta Felip,Delvys Rodriguez Abreu,Dolores Isla,Fabrice Barlesi,Olivier Molinier,Jeannick Madelaine,Clarisse Audigier-Valette,Sang-We Kim,Mustafa Ozguroglu,Mustafa Erman,Firas Benyamine Badin,Tarek Mekhail,Ronald J. Scheff,Jonathan W. Riess +16 more
TL;DR: Afatinib and pembrolizumab have demonstrated improvements in the outcomes of pts with SCC of the lung and are approved as monotherapy and are described as a selective and irreversible mechanism of action for SCC.
Journal ArticleDOI
Identification of super-exhausted T cells: A novel population predictive of response to immunotherapy.
Florent Peyraud,Jean-Philippe Guégan,Christophe Rey,Sophie Cousin,Guilhem Roubaud,Mathilde Cabart,Maxime Brunet,Ezogelin Oflazoglu Gruyters,Ariel Savina,Sylvestre Le Moulec,Bérangère Dadone-Montaudon,Fabrice Barlesi,Benjamin Besse,Yohann Loriot,Aurélien Marabelle,Jean-Charles Soria,Jean-Yves Scoazec,François Le Loarer,Alban Bessede,Antoine Italiano +19 more
TL;DR: The presence of super-exhausted T cells may represent a new predictive biomarker of response to ICB and pave the way for the development of effective ICB combinations.
Journal ArticleDOI
[Radiotherapy for oligometastatic non-small cell lung cancer patients].
TL;DR: In this paper, a review describes the definitions of oligometastatic disease, the main prospective findings including radiation therapy, and prospects for non-small cell lung cancer (NSCLC) patients.
Posted ContentDOI
Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis
Anne-Gaëlle Goubet,Anne-Gaëlle Goubet,Anne-Gaëlle Goubet,Agathe Dubuisson,Agathe Dubuisson,Arthur Geraud,François-Xavier Danlos,François-Xavier Danlos,Safae Terrisse,Safae Terrisse,Carolina Alves Costa Silva,Carolina Alves Costa Silva,Damien Drubay,Damien Drubay,Lea Touri,Marion Picard,Marion Picard,Marion Picard,Marine Mazzenga,Marine Mazzenga,Aymeric Silvin,Aymeric Silvin,Garett Dunsmore,Garett Dunsmore,Yacine Haddad,Yacine Haddad,Eugenie Pizzato,Eugenie Pizzato,Pierre Ly,Pierre Ly,Caroline Flament,Caroline Flament,Cléa Melenotte,Cléa Melenotte,Eric Solary,Michaela Fontenay,Michaela Fontenay,Gabriel Garcia,Corinne Balleyguier,Nathalie Lassau,Markus Maeurer,Mauro Piacentini,Claudia Grajeda-Iglesias,Nitharsshini Nirmalathasan,Fanny Aprahamian,Sylvère Durand,Oliver Kepp,Gladys Ferrere,Gladys Ferrere,Cassandra Thelemaque,Cassandra Thelemaque,Imran Lahmar,Imran Lahmar,Jean-Eudes Fahrner,Jean-Eudes Fahrner,Lydia Meziani,Lydia Meziani,Abdelhakim Ahmed-Belkacem,Nadia Saidani,Bernard La Scola,Didier Raoult,Stéphanie Gentile,Sébastien Cortaredona,Giuseppe Ippolito,Benjamin Lelouvier,Alain Roulet,Fabrice Andre,Fabrice Barlesi,Fabrice Barlesi,Jean-Charles Soria,Jean-Charles Soria,Caroline Pradon,Emmanuelle Gallois,Fanny Pommeret,Emeline Colomba,Florent Ginhoux,Florent Ginhoux,Suzanne Kazandjian,Arielle Elkrief,Arielle Elkrief,Bertrand Routy,Makoto Miyara,Guy Gorochov,Eric Deutsch,Laurence Albiges,Laurence Albiges,Annabelle Stoclin,Bertrand Gachot,Anne Florin,Mansouria Merad,Florian Scotté,Souad Assaad,Guido Kroemer,Jean-Yves Blay,Aurelien Marabelle,Frank Griscelli,Laurence Zitvogel,Lisa Derosa +97 more
TL;DR: In this article, the authors found that malignant disease favors the magnitude and duration of viral RNA shedding concomitant with prolonged serum elevations of type 1 IFN that anticorrelated with anti-RBD IgG antibodies.