F
Fabrizio Tagliavini
Researcher at Carlo Besta Neurological Institute
Publications - 422
Citations - 21532
Fabrizio Tagliavini is an academic researcher from Carlo Besta Neurological Institute. The author has contributed to research in topics: Frontotemporal dementia & Amyloid. The author has an hindex of 73, co-authored 380 publications receiving 18785 citations. Previous affiliations of Fabrizio Tagliavini include University of Parma & Laval University.
Papers
More filters
Journal ArticleDOI
Gerstmann‐Sträussler‐Scheinker disease II. Neurofibrillary tangles and plaques with PrP‐amyloid coexist in an affected family
Bernardino Ghetti,Fabrizio Tagliavini,Colin L. Masters,K. Beyreuther,Giorgio Giaccone,Laura Verga,Martin R. Farlow,P. M. Conneally,Stephen R. Dlouhy,B. Azzarelli,Orso Bugiani +10 more
TL;DR: The study of the 3rd and 4th cases that came to autopsy among the patients of this family indicates that a disturbance of the cytoskeleton might be part of the neuronal pathology of Gerstmann-Sträussler-Scheinker disease.
Journal ArticleDOI
Codeposition of Cystatin C with Amyloid-β Protein in the Brain of Alzheimer Disease Patients
Efrat Levy,Magdalena Sastre,Asok Kumar,Gloria Gallo,Pedro Piccardo,Bernardino Ghetti,Fabrizio Tagliavini +6 more
TL;DR: Analysis of brains of patients with Alzheimer disease (AD) revealed that the cysteine proteinase inhibitor cystatin C colocalizes with amyloid β-protein (Aβ) in parenchymal and vascular amyloids deposits.
Journal ArticleDOI
Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.
Adolfo Jiménez-Huete,Patricia M.-J. Lievens,Ruben Vidal,Pedro Piccardo,Bernardino Ghetti,Fabrizio Tagliavini,Blas Frangione,Frances Prelli +7 more
TL;DR: The data show that PrPC proteolytic processing of PrP may play an important role in the neurotropism and phenotypic expression of prion diseases, but it does not appear to participate in disease susceptibility.
Journal ArticleDOI
Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies.
Fabrizio Piazza,Steven M. Greenberg,Mario Savoiardo,Margherita Gardinetti,Luisa Chiapparini,Irina Raicher,Ricardo Nitrini,Hideya Sakaguchi,M. Brioschi,Giuseppe Billo,Antonio Colombo,Francesca Lanzani,Giuseppe Piscosquito,Maria Rita Carriero,Giorgio Giaccone,Fabrizio Tagliavini,Carlo Ferrarese,Jacopo C. DiFrancesco +17 more
TL;DR: The role of anti–amyloid β (Aβ) autoantibodies in the acute and remission phases of cerebral amyloid angiopathy–related inflammation is investigated.
Journal ArticleDOI
Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro.
Fabrizio Tagliavini,Gianluigi Forloni,Laura Colombo,Giacomina Rossi,Laura Girola,B. Canciani,Nadia Angeretti,Lidia Giampaolo,Elisa Peressini,Tazeen Awan,Luca De Gioia,Enzio Ragg,Orso Bugiani,Mario Salmona +13 more
TL;DR: It is shown that the antibiotic tetracycline binds to amyloid fibrils generated by synthetic peptides corresponding to residues 106-126 and 82-146 of human PrP and hinders assembly of these peptides into amyloids fibril.