F
Federico Lavorini
Researcher at University of Florence
Publications - 162
Citations - 5182
Federico Lavorini is an academic researcher from University of Florence. The author has contributed to research in topics: Inhaler & Medicine. The author has an hindex of 33, co-authored 137 publications receiving 3953 citations. Previous affiliations of Federico Lavorini include UniFi.
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Journal ArticleDOI
Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
TL;DR: It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.
Journal ArticleDOI
Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent.
Alessio Mazzoni,Lorenzo Salvati,Laura Maggi,Manuela Capone,Anna Vanni,Michele Spinicci,Jessica Mencarini,Roberto Caporale,Benedetta Peruzzi,Alberto Antonelli,Michele Trotta,Lorenzo Zammarchi,Luca Ciani,Leonardo Gori,Chiara Lazzeri,Andrea Matucci,Alessandra Vultaggio,Oliviero Rossi,Fabio Almerigogna,Paola Parronchi,Paolo Fontanari,Federico Lavorini,Adriano Peris,Gian Maria Rossolini,Alessandro Bartoloni,Sergio Romagnani,Francesco Liotta,Francesco Annunziato,Lorenzo Cosmi +28 more
TL;DR: The association between IL-6 serum levels and the impairment of cytotoxic activity suggests the possibility that targeting this cytokine may restore anti-viral mechanisms.
Journal ArticleDOI
The first tissue-engineered airway transplantation: 5-year follow-up results
Alessandro Gonfiotti,Massimo Osvaldo Jaus,Daniel Barale,Silvia Baiguera,Camilla E. Comin,Federico Lavorini,Giovanni A. Fontana,Oriol Sibila,Giovanni Rombolà,Philipp Jungebluth,Paolo Macchiarini +10 more
TL;DR: Clinical results provide evidence that a tissue-engineering strategy including decellularisation of a human trachea, autologous epithelial and stem-cell culture and differentiation, and cell-scaffold seeding with a bioreactor is safe and promising.
Journal ArticleDOI
Inhaler Errors in the CRITIKAL Study: Type, Frequency, and Association with Asthma Outcomes
David Price,Miguel Román-Rodríguez,R. Brett McQueen,Sinthia Bosnic-Anticevich,Victoria Carter,Kevin Gruffydd-Jones,John Haughney,Svein Høegh Henrichsen,Catherine Hutton,Antonio Infantino,Federico Lavorini,Lisa M Law,Karin Lisspers,Alberto Papi,Dermot Ryan,Björn Ställberg,Thys van der Molen,Henry Chrystyn +17 more
TL;DR: Specific inhaler errors have been identified as critical errors, evidenced by frequency and association with asthma outcomes, and Asthma management should target inhaler training to reduce key critical errors.
Journal ArticleDOI
Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes
Omar S. Usmani,Federico Lavorini,Jonathan Marshall,W. Dunlop,Louise Heron,Emily Farrington,Richard Dekhuijzen +6 more
TL;DR: Wide variations in how critical errors are defined are shown, and the evidence shows an important association between inhaler errors and worsened health outcomes, and a need for a consensus on defining critical and non-critical errors.