F
François Vingerhoets
Researcher at University Hospital of Lausanne
Publications - 119
Citations - 7379
François Vingerhoets is an academic researcher from University Hospital of Lausanne. The author has contributed to research in topics: Deep brain stimulation & Parkinson's disease. The author has an hindex of 44, co-authored 119 publications receiving 6790 citations. Previous affiliations of François Vingerhoets include University of Lausanne & Geneva College.
Papers
More filters
Journal ArticleDOI
VPS35 Mutations in Parkinson Disease
Carles Vilariño-Güell,Christian Wider,Owen A. Ross,Justus C. Dachsel,Jennifer M. Kachergus,Sarah Lincoln,Alexandra I. Soto-Ortolaza,Stephanie A. Cobb,Greggory J. Wilhoite,Justin A. Bacon,Behrouz Bahareh Behrouz,Heather L. Melrose,Emna Hentati,Andreas Puschmann,Andreas Puschmann,Daniel M. Evans,Elizabeth Conibear,Wyeth W. Wasserman,Jan O. Aasly,Pierre R. Burkhard,Ruth Djaldetti,Joseph Ghika,Fayçal Hentati,Anna Krygowska-Wajs,Timothy Lynch,Timothy Lynch,Eldad Melamed,Alex Rajput,Ali H. Rajput,Alessandra Solida,Ruey-Meei Wu,Ryan J. Uitti,Zbigniew K. Wszolek,François Vingerhoets,Matthew J. Farrer,Matthew J. Farrer +35 more
TL;DR: This study implicates disruption of VPS35 and retromer-mediated trans-membrane protein sorting, rescue, and recycling in the neurodegenerative process leading to PD.
Journal ArticleDOI
Gait assessment in Parkinson's disease: toward an ambulatory system for long-term monitoring
A. Salarian,H. Russmann,François Vingerhoets,Catherine Dehollain,Y. Blanc,Pierre Burkhard,Kamiar Aminian +6 more
TL;DR: The method provides a simple yet effective way of ambulatory gait analysis in PD patients with results confirming those obtained from much more complex and expensive methods used in gait labs.
Journal ArticleDOI
How do parkinsonian signs return after discontinuation of subthalamic DBS
P Temperli,J. Ghika,Jean-Guy Villemure,Pierre R. Burkhard,Julien Bogousslavsky,François Vingerhoets +5 more
TL;DR: STN DBS may act by different mechanisms on the four major parkinsonian signs, with a fast worsening of tremor within minutes, followed by a smoother, slower worsening of bradykinesia and rigidity over half an hour to an hour, and finally a slow and steady worsening of axial signs over 3 to 4 hours.
Journal ArticleDOI
Quantification of Tremor and Bradykinesia in Parkinson's Disease Using a Novel Ambulatory Monitoring System
TL;DR: Evidence is provided that objective, accurate and simultaneous assessment of tremor and bradykinesia can be achieved in free moving PD patients during their daily activities.
Journal ArticleDOI
Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients.
Alexandre Berney,François Vingerhoets,A. Perrin,Patrice Guex,Jean-Guy Villemure,Pierre R. Burkhard,Chawki Benkelfat,J. Ghika +7 more
TL;DR: In six patients with subthalamic deep brain stimulation in PD, mood state worsened significantly, and three were transiently suicidal despite clear motor improvement.