Alessandra Solida

TL;DR: This study implicates disruption of VPS35 and retromer-mediated trans-membrane protein sorting, rescue, and recycling in the neurodegenerative process leading to PD.

TL;DR: It is suggested that MMN enhancement may precede changes to indices of clinical severity, highlighting the possible utility AEPs as a biomarker of treatment efficacy, and the improvement of this functional marker may indicate an important pathway towards new therapeutic strategies that target glutathione dysregulation in schizophrenia.

TL;DR: Oxidative stress could be involved in the pathophysiology of schizophrenia, a major psychiatric disorder, and the gene of the key GSH-synthesizing enzyme, glutamate cysteine ligase modifier (GCLM) subunit, is strongly associated with schizophrenia.

TL;DR: The Treatment and Early Intervention in Psychosis Program-Lausanne is a comprehensive 3-year programme composed of an outpatient clinic based on assertive case management; a specialized inpatient unit; and an intensive mobile team, connected for research to the Center for Psychiatric Neuroscience as mentioned in this paper.

TL;DR: This study rules out the previously reported DYT14 locus as a cause of disease, as a novel multiexonic deletion was identified in GCH1, a multigenerational Swiss family with dopa-responsive dystonia.