F
Franz Hofmann
Researcher at Technische Universität München
Publications - 477
Citations - 51857
Franz Hofmann is an academic researcher from Technische Universität München. The author has contributed to research in topics: Protein kinase A & Voltage-dependent calcium channel. The author has an hindex of 113, co-authored 471 publications receiving 49938 citations. Previous affiliations of Franz Hofmann include Ludwig Maximilian University of Munich & Heidelberg University.
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Journal ArticleDOI
International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels
William A. Catterall,K. G. Chandy,David E. Clapham,George A. Gutman,Franz Hofmann,Anthony J. Harmar,Darrell R. Abernethy,Michael Spedding +7 more
TL;DR: This issue of Pharmacological Reviews includes a new venture in the collaboration between the International Union of Pharmacology (IUPHAR) and the American Society for Pharmacology and Experimental Therapeutics (ASPET), in that a new classification of voltage-gated ion channels is outlined.
Journal ArticleDOI
Nomenclature of voltage-gated sodium channels.
Alan L. Goldin,Robert L. Barchi,John H. Caldwell,Franz Hofmann,James R. Howe,John C. Hunter,Roland G. Kallen,Gail Mandel,Miriam H. Meisler,Yoheved Berwald Netter,Masahara Noda,Michael M. Tamkun,Steven G. Waxman,John N. Wood,William A. Catterall +14 more
TL;DR: The present alphabetical nomenclature does not reveal the structural relationships among the α1 subunits of Ca2+ channels, but it is apparent that these two alphabeticals will overlap at α1L, which may not mediate an L-type Ca2- current and therefore may create confusion.
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Patient-specific induced pluripotent stem-cell models for long-QT syndrome.
Alessandra Moretti,Milena Bellin,Andrea Welling,Christian Jung,Jason T. Lam,Lorenz Bott-Flügel,Tatjana Dorn,Alexander Goedel,Christian Höhnke,Franz Hofmann,Melchior Seyfarth,Daniel Sinnecker,Albert Schömig,Karl-Ludwig Laugwitz +13 more
TL;DR: It was shown that myocytes derived from patients with long-QT syndrome type 1 had an increased susceptibility to catecholamine-induced tachyarrhythmia and that beta-blockade attenuated this phenotype.
Journal ArticleDOI
Melanopsin and rod/cone photoreceptive systems account for all major accessory visual functions in mice.
Samer Hattar,Robert J. Lucas,Nicholas Mrosovsky,Stewart Thompson,Ronald H. Douglas,Mark W. Hankins,Janis Lem,Martin Biel,Franz Hofmann,Russell G. Foster,King Wai Yau +10 more
TL;DR: The rod–cone and melanopsin systems together seem to provide all of the photic input for these accessory visual functions such as pupillary light reflex and circadian photo-entrainment.
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A family of hyperpolarization-activated mammalian cation channels
TL;DR: The molecular cloning and functional expression of the gene encoding a hyperpolarization-activated cation channel (HAC1) that is present in brain and heart is reported, and this channel exhibits the general properties of Ih channels.