scispace - formally typeset
M

Miriam H. Meisler

Researcher at University of Michigan

Publications -  206
Citations -  17403

Miriam H. Meisler is an academic researcher from University of Michigan. The author has contributed to research in topics: Gene & Sodium channel. The author has an hindex of 58, co-authored 201 publications receiving 15508 citations. Previous affiliations of Miriam H. Meisler include Leeds Teaching Hospitals NHS Trust.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Nomenclature of voltage-gated sodium channels.

Alan L. Goldin, +14 more
- 01 Mar 2000 - 
TL;DR: The present alphabetical nomenclature does not reveal the structural relationships among the α1 subunits of Ca2+ channels, but it is apparent that these two alphabeticals will overlap at α1L, which may not mediate an L-type Ca2- current and therefore may create confusion.
Journal ArticleDOI

Mutation of the Ca2+ Channel β Subunit Gene Cchb4 Is Associated with Ataxia and Seizures in the Lethargic (lh) Mouse

Daniel L. Burgess, +3 more
- 07 Feb 1997 - 
TL;DR: The lethargic phenotype is the first example of a mammalian neurological disease caused by an inherited defect in a non-pore-forming subunit of a voltage-gated ion channel.
Journal ArticleDOI

Clinical application of exome sequencing in undiagnosed genetic conditions

Anna C. Need, +7 more
- 01 Jun 2012 - 
TL;DR: This study provides evidence that next-generation sequencing can have high success rates in a clinical setting, but also highlights key challenges, and suggests that the presentation of known Mendelian conditions may be considerably broader than currently recognised.
Journal ArticleDOI

Altered Subthreshold Sodium Currents and Disrupted Firing Patterns in Purkinje Neurons of Scn8a Mutant Mice

Indira M. Raman, +3 more
- 01 Oct 1997 - 
TL;DR: Both spontaneous firing and evoked bursts of spikes were diminished in cells from null and jolting mice, and apparently Scn8a channels carry most subthreshold sodium current and are crucial for repetitive firing.