Journal ArticleDOI
Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.
Lila Bouadma,Charles-Edouard Luyt,Florence Tubach,Christophe Cracco,Antonio Alvarez,Carole Schwebel,Frédérique Schortgen,Sigismond Lasocki,Benoit Veber,Monique Dehoux,Maguy Bernard,Blandine Pasquet,Bernard Regnier,Christian Brun-Buisson,Jean Chastre,Michel Wolff +15 more
TLDR
A procalcitonin-guided strategy to treat suspected bacterial infections in non-surgical patients in intensive care units could reduce antibiotic exposure and selective pressure with no apparent adverse outcomes.About:
This article is published in The Lancet.The article was published on 2010-02-06. It has received 980 citations till now. The article focuses on the topics: Intensive care & Procalcitonin.read more
Citations
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Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia the official statement of the American Thoracic Society and the Infectious Disease Society of America (特集 救急診療ガイドライン) -- (海外のガイドライン)
TL;DR: The Methodology used to Prepare the Guideline Epidemiology Incidence Etiology and Recommendations for Assessing Response to Therapy Suggested Performance Indicators is summarized.
Journal ArticleDOI
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society
Andre C. Kalil,Mark L. Metersky,Michael Klompas,John Muscedere,Daniel A. Sweeney,Lucy B. Palmer,Lena M. Napolitano,Naomi P. O'Grady,John G. Bartlett,Jordi Carratalà,Ali A. El Solh,Santiago Ewig,Paul D. Fey,Thomas M. File,Marcos I. Restrepo,Jason A. Roberts,Jason A. Roberts,Grant W. Waterer,Peggy E. Cruse,Shandra L Knight,Jan Brozek +20 more
TL;DR: These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), including specialists in infectious diseases, pulmonary diseases, critical care, and surgeons, anesthesiologists, hospitalists, and any clinicians and healthcare providers caring for hospitalized patients with nosocomial pneumonia.
Journal ArticleDOI
Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America
Tamar F. Barlam,Tamar F. Barlam,Sara E. Cosgrove,Lilian M. Abbo,Conan MacDougall,Audrey N. Schuetz,Edward Septimus,Arjun Srinivasan,Timothy H. Dellit,Yngve Falck-Ytter,Neil O. Fishman,Cindy W. Hamilton,Timothy C. Jenkins,Pamela A. Lipsett,Preeti N. Malani,Larissa S May,Gregory J. Moran,Melinda M. Neuhauser,Jason G. Newland,Christopher A. Ohl,Matthew H. Samore,Susan K. Seo,Kavita K. Trivedi +22 more
TL;DR: These recommendations address the best approaches for antibiotic stewardship programs to influence the optimal use of antibiotics.
Journal ArticleDOI
Interventions to improve antibiotic prescribing practices for hospital inpatients
Peter Davey,Charis Marwick,Claire Scott,Esmita Charani,Kirsty McNeil,Erwin M. Brown,Ian M. Gould,Craig R Ramsay,Susan Michie +8 more
TL;DR: This systematic review of interventions to improve antibiotic prescribing to hospital inpatients showed interventions to be associated with improvement in prescribing according to antibiotic policy in routine clinical practice, with 70% of interventions being hospital-wide compared with 31% for RCTs.
Journal ArticleDOI
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
Laura Evans,Andrew Rhodes,Waleed Alhazzani,Massimo Antonelli,Craig M. Coopersmith,Craig French,Flávia Ribeiro Machado,Lauralyn McIntyre,Marlies Ostermann,Hallie C. Prescott,Christa Schorr,Steven Q. Simpson,W. Joost Wiersinga,Fayez Alshamsi,Derek C. Angus,Yaseen M. Arabi,Luciano Cesar Pontes Azevedo,Richard Beale,Gregory J. Beilman,Emilie P. Belley-Côté,Lisa Burry,Maurizio Cecconi,John Centofanti,Angel Coz Yataco,Jan De Waele,R. Phillip Dellinger,Kent Doi,Bin Du,Elisa Estenssoro,Ricard Ferrer,Charles D. Gomersall,Carol L. Hodgson,Morten Hylander Møller,Theodore J. Iwashyna,Shevin T. Jacob,Ruth M. Kleinpell,Michael Klompas,Michael Klompas,Younsuck Koh,Anand Kumar,Arthur Kwizera,Suzana Margareth Lobo,Henry Masur,Steven McGloughlin,Sangeeta Mehta,Yatin Mehta,Mervyn Mer,Mark E. Nunnally,Simon Oczkowski,Tiffany M. Osborn,Elizabeth Papathanassoglou,Anders Perner,Michael A. Puskarich,Jason A. Roberts,William D. Schweickert,Maureen A. Seckel,Jonathan E. Sevransky,Charles L. Sprung,Charles L. Sprung,Tobias Welte,Janice L. Zimmerman,Mitchell M. Levy +61 more
TL;DR: The Surviving Sepsis Campaign (SSC) guidelines provide evidence-based recommendations on the recognition and management of sepsis and its complications as discussed by the authors, which are either strong or weak, or in the form of best practice statements.
References
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Journal ArticleDOI
Longitudinal data analysis for discrete and continuous outcomes.
Scott L. Zeger,Kung-Yee Liang +1 more
TL;DR: A class of generalized estimating equations (GEEs) for the regression parameters is proposed, extensions of those used in quasi-likelihood methods which have solutions which are consistent and asymptotically Gaussian even when the time dependence is misspecified as the authors often expect.
Journal ArticleDOI
Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults
Lionel A. Mandell,Richard G. Wunderink,Antonio Anzueto,John G. Bartlett,G. Douglas Campbell,Nathan C. Dean,Nathan C. Dean,Scott F. Dowell,Daniel M. Musher,Daniel M. Musher,Michael S. Niederman,Michael S. Niederman,Antoni Torres,Cynthia G. Whitney,Michael E. DeBakey Veterans +14 more
TL;DR: This work presents a meta-analyses of the immune system’s response to chronic obstructive pulmonary disease and shows clear patterns of decline in the immune systems of elderly patients with compromised immune systems.
Journal ArticleDOI
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Anand Kumar,Daniel Roberts,Kenneth E. Wood,Bruce Light,Joseph E. Parrillo,Satendra Sharma,Robert Suppes,Daniel Feinstein,Sergio Zanotti,Leo Taiberg,David A. Gurka,Aseem Kumar,Mary Cheang +12 more
TL;DR: Effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock.
Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia the official statement of the American Thoracic Society and the Infectious Disease Society of America (特集 救急診療ガイドライン) -- (海外のガイドライン)
TL;DR: The Methodology used to Prepare the Guideline Epidemiology Incidence Etiology and Recommendations for Assessing Response to Therapy Suggested Performance Indicators is summarized.
Journal ArticleDOI
Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study
Jl Vincent,A. de Mendonça,Francis Cantraine,Rui Moreno,Jukka Takala,Pm Suter,Cl Sprung,Francis Colardyn,S Blecher +8 more
TL;DR: In this paper, the authors evaluated the use of the Sequential Organ Failure Assessment (SOFA) score in assessing the incidence and severity of organ dysfunction in critically ill patients in ICU.
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