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Journal ArticleDOI

Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study

TLDR
The use of this preparation of hydroxyethylstarch as a plasma-volume expander is an independent risk factor for ARF in patients with severe sepsis or septic shock.
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This article is published in The Lancet.The article was published on 2001-03-24. It has received 687 citations till now. The article focuses on the topics: Renal function & Renal replacement therapy.

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Citations
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KDIGO clinical practice guidelines for acute kidney injury.

TL;DR: The guidelines focused on 4 key domains: (1) AKI definition, (2) prevention and treatment of AKI, (3) contrastinduced AKI (CI-AKI) and (4) dialysis interventions for the treatment ofAKI.

Surviving sepsis campaign: international guidelines for the management of severe sepsis and septic shock: 2008

TL;DR: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, the GRADE system was used to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations.
References
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Journal ArticleDOI

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

TL;DR: An American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference was held in Northbrook in August 1991 with the goal of agreeing on a set of definitions that could be applied to patients with sepsis and its sequelae as mentioned in this paper.
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A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

J R Le Gall, +2 more
- 22 Dec 1993 - 
TL;DR: The SAPS II, based on a large international sample of patients, provides an estimate of the risk of death without having to specify a primary diagnosis, and is a starting point for future evaluation of the efficiency of intensive care units.
Journal ArticleDOI

The Natural History of the Systemic Inflammatory Response Syndrome (SIRS): A Prospective Study

TL;DR: This prospective epidemiologic study of SIRS and related conditions provides the first evidence of a clinical progression from SirS to sepsis to severe sepsi and septic shock, and stepwise increases in mortality rates in the hierarchy.
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Gram-Negative Bacteremia: I. Etiology and Ecology

TL;DR: This report reviews the experience with Gram-negative bacteremia during an 8-year period at the University of Illinois Research and Educational Hospitals and determines the etiology and some aspects of the ecology of these infections.
Journal ArticleDOI

Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis.

TL;DR: Patients with clinically suspected sepsis but without microbiological documentation and patients with documented infection share common risk factors and are at similarly high risk of death.
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