F
Friederike Reuter
Researcher at German Cancer Research Center
Publications - 3
Citations - 245
Friederike Reuter is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Stress granule & mTORC1. The author has an hindex of 3, co-authored 3 publications receiving 77 citations.
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Journal ArticleDOI
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
Ahmed Sadik,Luis F. Somarribas Patterson,Selcen Öztürk,Soumya R. Mohapatra,Verena Panitz,Philipp F Secker,Pauline Pfänder,Stefanie Loth,Heba Salem,Mirja Tamara Prentzell,Bianca Berdel,Murat Iskar,Erik Faessler,Friederike Reuter,Isabelle Kirst,Verena Kalter,Kathrin I. Foerster,Evelyn Jäger,Carina Ramallo Guevara,Mansour Sobeh,Thomas Hielscher,Gernot Poschet,Annekathrin Reinhardt,Jessica C. Hassel,Marc Zapatka,Udo Hahn,Andreas von Deimling,Carsten Hopf,Rita Schlichting,Beate I. Escher,Jürgen Burhenne,Walter E. Haefeli,Naveed Ishaque,Alexander Böhme,Sascha Schäuble,Kathrin Thedieck,Saskia Trump,Martina Seiffert,Christiane A. Opitz +38 more
TL;DR: A pan-tissue AHR signature revealed that across 32 tumor entities, interleukin-4-induced-1 (IL4I1) associates more frequently with AHR activity than IDO1 or TDO2, hitherto recognized as the main Trp-catabolic enzymes.
Journal ArticleDOI
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
Mirja Tamara Prentzell,Ulrike Rehbein,Ulrike Rehbein,Ulrike Rehbein,Marti Cadena Sandoval,Marti Cadena Sandoval,Ann-Sofie De Meulemeester,Ralf Baumeister,Laura Brohée,Bianca Berdel,Mathias Bockwoldt,Bernadette Carroll,Suvagata Roy Chowdhury,Andreas von Deimling,Andreas von Deimling,Constantinos Demetriades,Constantinos Demetriades,Gianluca Figlia,Gianluca Figlia,Mariana E. G. de Araujo,Alexander Martin Heberle,Alexander Martin Heberle,Ines Heiland,Birgit Holzwarth,Lukas A. Huber,Jacek Jaworski,Magdalena Kedra,Katharina Kern,Andrii Kopach,Viktor I. Korolchuk,Ineke van 't Land-Kuper,Ineke van 't Land-Kuper,Matylda Macias,Mark Nellist,Wilhelm Palm,Stefan Pusch,Stefan Pusch,Jose Miguel Ramos Pittol,Michèle Reil,Anja Reintjes,Friederike Reuter,Julian R. Sampson,Chloë Scheldeman,Aleksandra Siekierska,Eduard Stefan,Aurelio A. Teleman,Aurelio A. Teleman,Laura E. Thomas,Omar Torres-Quesada,Saskia Trump,Hannah West,Peter de Witte,Sandra Woltering,Teodor E. Yordanov,Teodor E. Yordanov,Justyna Zmorzynska,Christiane A. Opitz,Christiane A. Opitz,Kathrin Thedieck,Kathrin Thedieck,Kathrin Thedieck +60 more
TL;DR: In this article, GTPase-activating protein-binding proteins 1 and 2 (G3BP1 and G3BP2, respectively) are reported to reside at the cytoplasmic surface of lysosomes.
Posted ContentDOI
G3BP1 tethers the TSC complex to lysosomes and suppresses mTORC1 in the absence of stress granules
Mirja Tamara Prentzell,Ulrike Rehbein,Ulrike Rehbein,Marti Cadena Sandoval,Marti Cadena Sandoval,De Wildeman Stefaan M A,Ralf Baumeister,Laura Brohée,Bianca Berdel,Mathias Bockwoldt,Bernadette Carroll,von Deimling A,Constantinos Demetriades,Constantinos Demetriades,Gianluca Figlia,Gianluca Figlia,Alexander Martin Heberle,Alexander Martin Heberle,Ines Heiland,Birgit Holzwarth,Lukas A. Huber,Jacek Jaworski,Katharina Kern,Kopach A,Viktor I. Korolchuk,van ’t Land-Kuper I,van ’t Land-Kuper I,Matylda Macias,Mark Nellist,Stefan Pusch,Reil M,Anja Reintjes,Friederike Reuter,Chloë Scheldeman,Eduard Stefan,Aurelio A. Teleman,Aurelio A. Teleman,Omar Torres-Quesada,Saskia Trump,de Witte P,Teodor E. Yordanov,Teodor E. Yordanov,Christiane A. Opitz,Christiane A. Opitz,Kathrin Thedieck,Kathrin Thedieck,Kathrin Thedieck +46 more
TL;DR: It is reported that in the absence of SG, G3BP1 acts as lysosomal anchor of the Tuberous Sclerosis Complex (TSC) protein complex, tethers the TSC complex to lysoomes, and suppresses signaling through the metabolic master regulator mTORC1.