G
Gad Getz
Researcher at Weizmann Institute of Science
Publications - 24
Citations - 2997
Gad Getz is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Breast cancer & Cluster analysis. The author has an hindex of 15, co-authored 24 publications receiving 2937 citations.
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Journal ArticleDOI
Coupled two-way clustering analysis of gene microarray data
TL;DR: An algorithm, based on iterative clustering, that performs an algorithm to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant partitions emerge.
Journal ArticleDOI
Outcome signature genes in breast cancer: is there a unique set?
TL;DR: It is shown that the resulting set of genes is not unique; it is strongly influenced by the subset of patients used for gene selection, and the correlations fluctuate strongly when measured over different subsets of patients.
Journal ArticleDOI
DNA microarrays identification of primary and secondary target genes regulated by p53.
Karuppiah Kannan,Ninette Amariglio,Gideon Rechavi,Jasmine Jakob-Hirsch,Itai Kela,Naftali Kaminski,Gad Getz,Eytan Domany,David Givol +8 more
TL;DR: The results suggest that p53 activates concerted opposing signals and exerts its effect through a diverse network of transcriptional changes that collectively alter the cell phenotype in response to stress.
Journal Article
Classification of Human Astrocytic Gliomas on the Basis of Gene Expression A Correlated Group of Genes with Angiogenic Activity Emerges As a Strong Predictor of Subtypes
Sophie Godard,Gad Getz,Mauro Delorenzi,Pierre Farmer,Hiroyuki Kobayashi,Isabelle Desbaillets,Michimasa Nozaki,Annie-Claire Diserens,Marie-France Hamou,Pierre-Yves Dietrich,Luca Regli,Robert C. Janzer,Philipp Bucher,Roger Stupp,Nicolas de Tribolet,Eytan Domany,Monika E. Hegi,Monika E. Hegi +17 more
TL;DR: It is demonstrated that human gliomas can be differentiated according to their gene expression, and found that low-grade astrocytoma have the most specific and similar expression profiles, whereas primary glioblastoma exhibit much larger variation between tumors.
Journal ArticleDOI
Outcome signature genes in breast cancer: is there a unique set?
TL;DR: It is shown that in fact the resulting set of genes is not unique; it is strongly influenced by the subset of patients used for gene selection, and the correlations fluctuate strongly when measured over different subsets of patients.