G
Gennaro Marino
Researcher at University of Naples Federico II
Publications - 230
Citations - 7590
Gennaro Marino is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Pseudoalteromonas haloplanktis & Mass spectrometry. The author has an hindex of 44, co-authored 220 publications receiving 7104 citations. Previous affiliations of Gennaro Marino include Martin Luther University of Halle-Wittenberg & Università degli Studi Suor Orsola Benincasa.
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Journal ArticleDOI
Coping with cold: The genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125
Claudine Médigue,Evelyne Krin,Géraldine Pascal,Valérie Barbe,Andreas Bernsel,Philippe N. Bertin,Frankie Cheung,Stéphane Cruveiller,Salvino D'Amico,Angela Duilio,Gang Fang,Georges Feller,Christine Ho,Sophie Mangenot,Gennaro Marino,Johan Nilsson,Ermenegilda Parrilli,Eduardo P. C. Rocha,Zoé Rouy,Agnieszka Sekowska,Maria Luisa Tutino,David Vallenet,Gunnar von Heijne,Antoine Danchin +23 more
TL;DR: The analysis of the genome sequence of the fast growing Antarctica bacterium Pseudoalteromonas haloplanktis TAC125 finds that it copes with the increased solubility of oxygen at low temperature by multiplying dioxygen scavenging while deleting whole pathways producing reactive oxygen species.
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Leptin induces direct vasodilation through distinct endothelial mechanisms.
Giuseppe Lembo,Carmine Vecchione,Luigi Fratta,Gennaro Marino,Valentina Trimarco,Giulia d'Amati,Bruno Trimarco +6 more
TL;DR: Leptin-evoked vasorelaxation evoked by leptin is heterogeneous and related to the vascular bed, and the inhibition of nitric oxide synthase by NG-nitro-L-arginine-methyl ester does not modify blood pressure response to leptin, suggesting a predominant role of the EDHF mechanism in the hypotensive effect of leptin.
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Melusin, a muscle-specific integrin β1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
Mara Brancaccio,Luigi Fratta,Antonella Notte,Emilio Hirsch,Roberta Poulet,Simona Guazzone,Marika De Acetis,Carmine Vecchione,Gennaro Marino,Fiorella Altruda,Lorenzo Silengo,Guido Tarone,Giuseppe Lembo +12 more
TL;DR: Analysis of intracellular signaling events induced by pressure overload indicated that phosphorylation of glycogen synthase kinase-3 β (GSK-3β) was specifically blunted in melusin-null hearts, which prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress.
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Emilin1 Links TGF-β Maturation to Blood Pressure Homeostasis
Luca Zacchigna,Carmine Vecchione,Antonella Notte,Michelangelo Cordenonsi,Sirio Dupont,Silvia Maretto,Giuseppe Cifelli,Alessandra Ferrari,Angelo Maffei,Carla Fabbro,Paola Braghetta,Gennaro Marino,Giulio Selvetella,Alessandra Aretini,Claudio Colonnese,Umberto Bettarini,Giovanni Russo,Sandra Soligo,Maddalena Adorno,Paolo Bonaldo,Dino Volpin,Stefano Piccolo,Giuseppe Lembo,Giorgio M. Bressan +23 more
TL;DR: An unprecedented link between TGF-beta signaling and arterial hypertension is reported based on the analysis of mice mutant for Emilin1, a cysteine-rich secreted glycoprotein expressed in the vascular tree.
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Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’
S. Maurelli,Tiziana Bisogno,Luciano De Petrocellis,Aldo Di Luccia,Gennaro Marino,Vincenzo Di Marzo +5 more
TL;DR: ‘anandamide amidohydrolase’ enzymes, such as that characterised in this study, may be used by neuronal cells also to hydrolyse the novel sleep‐inducing factor oleoyl‐amide.