Giorgio Battaglia

TL;DR: Focal cortical dysplasias (FCD) are localized regions of malformed cerebral cortex and are very frequently associated with epilepsy in both children and adults.

TL;DR: This work identifies AFG3L2 as a novel cause of dominant neurodegenerative disease and indicates a previously unknown role for this component of the mitochondrial protein quality control machinery in protecting the human cerebellum against neurodegenersation.

TL;DR: Clinical, MRI, and electrophysiologic findings in 54 PNH patients are analyzed to reevaluate the classification of PNH, relate the anatomic features to epileptic outcome, and ascertain the contribution of P NH nodules to the onset of epileptic discharges.

TL;DR: FESD is a feasible, safe, and effective treatment for symptomatic ZD, with low adverse event and recurrence rates, including an in-depth evaluation of its efficacy, safety, and limitations.

TL;DR: Pharmacological blockade of NR2B-containing NMDARs by ifenprodil administration during epileptogenesis significantly reduced pyramidal cell loss in the hippocampus, showing that the observed post-translational and cellular changes ofNR2B subunit contribute to excitotoxicity.