P
Paolo Plevani
Researcher at University of Milan
Publications - 108
Citations - 8022
Paolo Plevani is an academic researcher from University of Milan. The author has contributed to research in topics: DNA replication & DNA repair. The author has an hindex of 48, co-authored 108 publications receiving 7783 citations. Previous affiliations of Paolo Plevani include University of Pavia.
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Journal ArticleDOI
The complete DNA sequence of yeast chromosome III.
Stephen G. Oliver,Q. J. M. van der Aart,M. L. Agostoni-Carbone,Michel Aigle,Lilia Alberghina,Despina Alexandraki,G. Antoine,Rashida Anwar,Juan P. G. Ballesta,Paule Bénit,Gilbert Berben,Elisabetta Bergantino,N. Biteau,P. A. Bolle,Monique Bolotin-Fukuhara,Anthony G. A. Brown,Alistair J. P. Brown,J. M. Buhler,C. Carcano,Giovanna Carignani,Håkan Cederberg,R. Chanet,Roland Contreras,Marc Crouzet,B. Daignan-Fornier,E. Defoor,M. Delgado,Jan Demolder,C. Doira,Evelyne Dubois,Bernard Dujon,A. Düsterhöft,D. Erdmann,M. Esteban,F. Fabre,Cécile Fairhead,Gérard Faye,Horst Feldmann,Walter Fiers,M. C. Francingues-Gaillard,L. Franco,Laura Frontali,H. Fukuhara,L. J. Fuller,P. Galland,Manda E. Gent,D. Gigot,Véronique Gilliquet,Glansdorff Nn,André Goffeau,M. Grenson,P. Grisanti,Leslie A. Grivell,M. de Haan,M. Haasemann,D. Hatat,Janet Hoenicka,Johannes H. Hegemann,C. J. Herbert,François Hilger,Stefan Hohmann,Cornelis P. Hollenberg,K. Huse,F. Iborra,K. J. Indje,K. Isono,C. Jacq,M. Jacquet,C. M. James,J. C. Jauniaux,Y. Jia,Alberto Jiménez,A. Kelly,U. Kleinhans,P Kreisl,G. Lanfranchi,C Lewis,C. G. vanderLinden,G Lucchini,K Lutzenkirchen,M.J. Maat,L. Mallet,G. Mannhaupet,Enzo Martegani,A. Mathieu,C. T. C. Maurer,David J. McConnell,R. A. McKee,F. Messenguy,Hans-Werner Mewes,Francis Molemans,M. A. Montague,M. Muzi Falconi,L. Navas,Carol S. Newlon,D. Noone,C. Pallier,L. Panzeri,Bruce M. Pearson,J. Perea,Peter Philippsen,A. Pierard,Rudi J. Planta,Paolo Plevani,B. Poetsch,Fritz M. Pohl,B. Purnelle,M. Ramezani Rad,S. W. Rasmussen,A. Raynal,Miguel Remacha,P. Richterich,Aki Roberts,F. Rodriguez,E. Sanz,I. Schaaff-Gerstenschlager,Bart Scherens,Bertold Schweitzer,Y. Shu,J. Skala,Piotr P. Slonimski,F. Sor,C. Soustelle,R. Spiegelberg,Lubomira Stateva,H. Y. Steensma,S. Steiner,Agnès Thierry,George Thireos,Maria Tzermia,L. A. Urrestarazu,Giorgio Valle,I. Vetter,J. C. van Vliet-Reedijk,Marleen Voet,Guido Volckaert,P. Vreken,H. Wang,John R. Warmington,D. von Wettstein,Barton Luke Wicksteed,C. Wilson,H. Wurst,G. Xu,A. Yoshikawa,Friedrich K. Zimmermann,J. G. Sgouros +146 more
TL;DR: The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined, which is the first complete sequence analysis of an entire chromosome from any organism.
Journal ArticleDOI
The DNA replication checkpoint response stabilizes stalled replication forks
Massimo Lopes,Cecilia Cotta-Ramusino,Achille Pellicioli,Giordano Liberi,Paolo Plevani,Marco Muzi-Falconi,Carol S. Newlon,Marco Foiani +7 more
TL;DR: It is shown that hydroxyurea-treated rad53 mutants accumulate unusual DNA structures at replication forks, and it is proposed that Rad53 prevents collapse of the fork when replication pauses.
Journal ArticleDOI
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
Achille Pellicioli,Chiara Lucca,Giordano Liberi,Federica Marini,Federica Marini,Massimo Lopes,Paolo Plevani,Alfredo Romano,Pier Paolo Di Fiore,Marco Foiani +9 more
TL;DR: The Saccharomyces cerevisiae Rad53 protein kinase is required for the execution of checkpoint arrest at multiple stages of the cell cycle and autophosphorylation activity depends on in trans phosphorylation mediated by Mec1 and does not require physical association with other proteins.
Journal ArticleDOI
The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.
TL;DR: The characterization of the temperature-sensitive pol12-T9 mutant allele demonstrates that the B subunit is required for in vivo DNA synthesis and correct progression through S phase, and reciprocal shift experiments indicate that the POL12 gene product plays an essential role at the early stage of chromosomal DNA replication, before the hydroxyurea-sensitive step.
Journal ArticleDOI
The DNA Damage Checkpoint Response Requires Histone H2B Ubiquitination by Rad6-Bre1 and H3 Methylation by Dot1
TL;DR: It is demonstrated that ubiquitination of histone H2B on lysine 123 by the Rad6-Bre1 complex, is necessary for activation of Rad53 kinase and cell cycle arrest and results suggest that histone modifications may have a role in checkpoint function by modulating the interactions of Rad9 with chromatin and active Mec1 kinase.