G
Giovanni Fabbrini
Researcher at Sapienza University of Rome
Publications - 318
Citations - 12735
Giovanni Fabbrini is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Parkinson's disease & Dystonia. The author has an hindex of 56, co-authored 287 publications receiving 11067 citations. Previous affiliations of Giovanni Fabbrini include National Institutes of Health.
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Journal ArticleDOI
Summary of the recommendations of the EFNS/MDS-ES review on therapeutic management of Parkinson's disease
Joaquim J. Ferreira,R. Katzenschlager,B.R. Bloem,Ubaldo Bonuccelli,David J. Burn,Günther Deuschl,Espen Dietrichs,Giovanni Fabbrini,A. Friedman,Petr Kanovsky,Vladimir S. Kostic,Alice Nieuwboer,Per Odin,Werner Poewe,O. Rascol,O. Rascol,Cristina Sampaio,Michael Schüpbach,Michael Schüpbach,Eduard Tolosa,Claudia Trenkwalder,Anthony H.V. Schapira,Alfredo Berardelli,Wolfgang H. Oertel +23 more
TL;DR: To summarize the 2010 EFNS/MDS‐ES evidence‐based treatment recommendations for the management of Parkinson's disease, this summary includes the treatmentRecommendations for early and late PD.
Journal ArticleDOI
Parkinson's disease: Autoimmunity and neuroinflammation
Armando De Virgilio,Antonio Greco,Giovanni Fabbrini,Maurizio Inghilleri,Maria Ida Rizzo,Andrea Gallo,Michela Conte,Chiara Rosato,Mario Ciniglio Appiani,Marco de Vincentiis +9 more
TL;DR: The past decade has provided evidence for a significant role of the immune system in PD pathogenesis, either through inflammation or an autoimmune response, and immune activation may be the cause of, rather than a response to, the observed neuronal loss.
Journal ArticleDOI
Pain as a Nonmotor Symptom of Parkinson Disease: Evidence From a Case-Control Study
Giovanni Defazio,Alfredo Berardelli,Giovanni Fabbrini,Davide Martino,E. Fincati,Antonio Fiaschi,Giuseppe Moretto,Giovanni Abbruzzese,Roberta Marchese,Ubaldo Bonuccelli,Paolo Del Dotto,Paolo Barone,Elisa De Vivo,Alberto Albanese,Angelo Antonini,Margherita Canesi,Leonardo Lopiano,Maurizio Zibetti,Giuseppe Nappi,Emilia Martignoni,Paolo Lamberti,Michele Tinazzi +21 more
TL;DR: In this article, a case-control study was conducted to determine whether pain is more frequent among people with Parkinson disease (PD) than among age-matched controls, using logistic regression models taking into account type of pain, time between pain and PD onset, and possible confounders.
Pain as a Nonmotor Symptom of Parkinson Disease
Giovanni Defazio,Alfredo Berardelli,Giovanni Fabbrini,Davide Martino,E. Fincati,Antonio Fiaschi,Giuseppe Moretto,Giovanni Abbruzzese,Roberta Marchese,Ubaldo Bonuccelli,Paolo Del Dotto,Paolo Barone,Elisa De Vivo,Alberto Albanese,Angelo Antonini,Margherita Canesi,Leonardo Lopiano,Maurizio Zibetti,Giuseppe Nappi,Emilia Martignoni,Paolo Lamberti,Michele Tinazzi +21 more
TL;DR: Data support the hypothesis that pain begins at clinical onset of PD or thereafter as a nonmotor feature of PD.
Journal ArticleDOI
Levodopa pharmacokinetic mechanisms and motor fluctuations in Parkinson's disease
TL;DR: Although symptom duration was the best predictor of the severity of untreated parkinsonism, levodopa dose correlated best with response half‐time, and may provide a quantitative index of central mechanisms that favor the development of the wearing‐off and on‐off phemonena.