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Giuseppe Balistreri
Researcher at University of Helsinki
Publications - 45
Citations - 2823
Giuseppe Balistreri is an academic researcher from University of Helsinki. The author has contributed to research in topics: Biology & Viral replication. The author has an hindex of 17, co-authored 29 publications receiving 1749 citations. Previous affiliations of Giuseppe Balistreri include ETH Zurich & University of Queensland.
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Journal ArticleDOI
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.
Ludovico Cantuti-Castelvetri,Ludovico Cantuti-Castelvetri,Ravi Ojha,Liliana D. Pedro,Liliana D. Pedro,Minou Djannatian,Minou Djannatian,Jonas Franz,Suvi Kuivanen,Franziska van der Meer,Katri Kallio,Tuğberk Kaya,Tuğberk Kaya,Tuğberk Kaya,Maria Anastasina,Maria Anastasina,Teemu Smura,Lev Levanov,Leonora Szirovicza,Allan Tobi,Hannimari Kallio-Kokko,Pamela Österlund,Merja Joensuu,Frederic A. Meunier,Sarah J. Butcher,Sarah J. Butcher,Martin Sebastian Winkler,Brit Mollenhauer,Ari Helenius,Ozgun Gokce,Tambet Teesalu,Tambet Teesalu,Tambet Teesalu,Jussi Hepojoki,Jussi Hepojoki,Olli Vapalahti,Christine Stadelmann,Giuseppe Balistreri,Giuseppe Balistreri,Mikael Simons,Mikael Simons +40 more
TL;DR: It is found that neuropilin-1 (NRP1), known to bind furin-cleaved substrates, significantly potentiates SARS-CoV-2 infectivity, an effect blocked by a monoclonal blocking antibody against NRP1.
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Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes
TL;DR: This work highlights both fundamental similarities and important differences in the processes that lead to the modified membrane compartments in cells infected by distinct groups of positive-sense RNA viruses.
Journal ArticleDOI
Single‐cell analysis of population context advances RNAi screening at multiple levels
Berend Snijder,Raphael Sacher,Pauli Rämö,Prisca Liberali,Karin Mench,Nina Wolfrum,Laura Burleigh,Cameron C. Scott,Monique H. Verheije,Jason Mercer,Stefan Moese,Thomas Heger,Kristina Theusner,Kristina Theusner,Andreas Jurgeit,David Lamparter,Giuseppe Balistreri,Mario Schelhaas,Cornelis A. M. de Haan,Varpu Marjomäki,Timo Hyypiä,Peter J. M. Rottier,Beate Sodeik,Mark Marsh,Jean Gruenberg,Ali Amara,Urs F. Greber,Ari Helenius,Lucas Pelkmans +28 more
TL;DR: It is found that accounting for indirect effects improves the consistency between siRNAs targeted against the same gene, and between replicate RNAi screens performed in different cell lines, in different labs, and with different siRNA libraries.
Journal ArticleDOI
Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin
Miriam Carolin Stoeber,Ina Karen Stoeck,Christine Hänni,Christopher K. E. Bleck,Giuseppe Balistreri,Ari Helenius +5 more
TL;DR: The Eps‐15 homology domain‐containing protein 2 (EHD2, anATPase) associated with the static population of PM caveolae likely plays a key role in adjusting the balance between PM functions of stationary Caveolae and the role of caveolai asvesicular carriers.
Journal ArticleDOI
The Host Nonsense-Mediated mRNA Decay Pathway Restricts Mammalian RNA Virus Replication
Giuseppe Balistreri,Peter Horvath,Christoph Schweingruber,David Zünd,Gerald M. McInerney,Andres Merits,Oliver Mühlemann,Claus M. Azzalin,Ari Helenius +8 more
TL;DR: Findings indicate that a cellular mRNA quality control mechanism serves as an intrinsic barrier to the translation of early viral proteins and the amplification of +RNA viruses in animal cells.