Tuğberk Kaya

TL;DR: It is found that neuropilin-1 (NRP1), known to bind furin-cleaved substrates, significantly potentiates SARS-CoV-2 infectivity, an effect blocked by a monoclonal blocking antibody against NRP1.

TL;DR: In this article , the authors used single-cell RNA-sequencing to identify interferon (IFN)-responsive oligodendrocytes, which localize in proximity to CD8 + T cells in aging white matter.

TL;DR: ADAM10 and ADAM17 are established as host cell factors for viral entry and syncytia formation and both proteases are defined as potential targets for antiviral drug development.

TL;DR: Safaiyan et al. as discussed by the authors proposed an enzymatic dissociation method for mouse brain that prevents dissociation artifacts and lowers technical variations with standardized steps, and tested this protocol on microdissected brain tissue of 3-week-to 24-month-old mice and obtained high-quality scRNA-seq results.

TL;DR: In this article , the effects of incremental and radical creativity on both product and process innovation by considering the moderating roles of knowledge sharing in intensity and quality are examined, and the differences in the impacts of incremental creativity with the moderations of organisational knowledge on product/process innovations between the service and manufacturing firms operating in Pakistan are presented.