Giuseppe Del Giudice

TL;DR: MTOR inhibition by RAD001 improves immune responses in elderly volunteers receiving an influenza vaccination, raising the possibility that mTOR inhibition may have beneficial effects on immunosenescence in the elderly.

TL;DR: This study supports a possible protective role of vegetable intake in the intestinal type of GC and the ACO and finds a negative but non significant association between citrus fruit intake and the cardia site while no association was observed with the non‐cardia site.

TL;DR: Total, red, and processed meat intakes were associated with an increased risk of gastric non-cardia cancer, especially in H. pylori antibody-positive subjects, but not with cardia gastric cancer.

TL;DR: Results support the use of adjuvants with flu vaccinations and could help expand coverage and decrease morbidity in the event of pandemic influenza and give vaccine makers the edge in a game of catch-up with dark horses.

TL;DR: While the unique anatomical predisposition of the facial nerve to compression suggests nasal delivery of neuronal-binding LT–derived adjuvants is inadvisable, their continued investigation as topical or mucosal adjuvant and antigens appears warranted on the basis of longstanding safety via oral, percutaneous, and other mucosal routes.