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Guixia Yu
Researcher at University of California, San Francisco
Publications - 44
Citations - 8309
Guixia Yu is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Gene & Zika virus. The author has an hindex of 24, co-authored 40 publications receiving 6058 citations. Previous affiliations of Guixia Yu include Cornell University.
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Journal ArticleDOI
CRISPR-Cas12-based detection of SARS-CoV-2.
James Paul Broughton,Xianding Deng,Guixia Yu,Clare L Fasching,Venice Servellita,Jasmeet Singh,Xin Miao,Jessica Streithorst,Andrea Granados,Alicia Sotomayor-Gonzalez,Kelsey C. Zorn,Allan Gopez,Elaine Hsu,Wei Gu,Steve Miller,Chao Yang Pan,Hugo Guevara,Debra A. Wadford,Janice S. Chen,Charles Y. Chiu +19 more
TL;DR: The CRISPR-based DETECTR assay provides a visual and faster alternative to the US Centers for Disease Control and Prevention SARS-CoV-2 real-time RT–PCR assay, with 95% positive predictive agreement and 100% negative predictive agreement.
Journal ArticleDOI
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Kayoko Yamada,Jun Lim,Joseph M. Dale,Huaming Chen,Huaming Chen,Paul Shinn,Paul Shinn,Curtis J. Palm,Audrey Southwick,Hank C. Wu,Christopher Kim,Christopher Kim,Michelle Nguyen,Paul K. Pham,Rosa Cheuk,Rosa Cheuk,George Karlin-Newmann,Shirley X. Liu,Bao Lam,Hitomi Sakano,Troy Wu,Guixia Yu,Molly Miranda,Hong L. Quach,Matthew Tripp,Charlie H. Chang,Jeong M. Lee,Mitsue J. Toriumi,Marie M. H. Chan,Carolyn C. Tang,Courtney Onodera,Justine M. Deng,Kenji Akiyama,Yasser Ansari,Takahiro Arakawa,Jenny Banh,Fumika Banno,Leah Bowser,Shelise Brooks,Piero Carninci,Qimin Chao,Nathan Choy,Akiko Enju,Andrew D. Goldsmith,Mani Gurjal,Nancy F. Hansen,Yoshihide Hayashizaki,Chanda Johnson-Hopson,Vickie Hsuan,Kei Iida,Meagan Karnes,Shehnaz Khan,Eric Koesema,Junko Ishida,Paul X. Jiang,Ted Jones,Jun Kawai,Asako Kamiya,Cristina C. Meyers,Maiko Nakajima,Mari Narusaka,Motoaki Seki,Tetsuya Sakurai,Masakazu Satou,Racquel Tamse,Maria Vaysberg,Erika Wallender,Cecilia Wong,Yuki Yamamura,Shiaulou Yuan,Kazuo Shinozaki,Ronald W. Davis,Athanasios Theologis,Joseph R. Ecker,Joseph R. Ecker +74 more
TL;DR: In this paper, a dual experimental strategy was used to verify and correct the initial genome sequence annotation of the reference plant Arabidopsis and identified 5817 novel transcription units including a substantial amount of antisense gene transcription, and 40 genes within the genetically defined centromeres.
Journal ArticleDOI
Functional Genomic Analysis of the AUXIN RESPONSE FACTOR Gene Family Members in Arabidopsis thaliana : Unique and Overlapping Functions of ARF7 and ARF19
Yoko Okushima,Paul J. Overvoorde,Kazunari Arima,Jose M. Alonso,April Chan,Charlie Chang,Joseph R. Ecker,Beth Hughes,Amy Lui,Diana Nguyen,Courtney Onodera,Hong Quach,Alison M. Smith,Guixia Yu,Athanasios Theologis +14 more
TL;DR: The identification and characterization of T-DNA insertion lines for 18 of the 23 ARF gene family members in Arabidopsis thaliana suggest that the ARF7 and ARF19 proteins play essential roles in auxin-mediated plant development by regulating both unique and partially overlapping sets of target genes.
Journal ArticleDOI
Actionable Diagnosis of Neuroleptospirosis by Next-Generation Sequencing
Michael R. Wilson,Samia N. Naccache,Erik Samayoa,Mark Biagtan,Hiba Bashir,Guixia Yu,Shahriar M. Salamat,Sneha Somasekar,Scot Federman,Steve Miller,Robert A. Sokolic,Elizabeth Garabedian,Fabio Candotti,Rebecca H. Buckley,Kurt D. Reed,Teresa L. Meyer,Christine M. Seroogy,Renee Galloway,Sheryl L Henderson,James E. Gern,Joseph L. DeRisi,Charles Y. Chiu +21 more
TL;DR: A 14-year-old boy with severe combined immunodeficiency presented three times to a medical facility over a period of 4 months with fever and headache that progressed to hydrocephalus and status epilepticus necessitating a medically induced coma, confirming evidence of Leptospira santarosai infection.
Journal ArticleDOI
Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis
Michael R. Wilson,Hannah A. Sample,Kelsey C. Zorn,Shaun Arevalo,Guixia Yu,John Neuhaus,Scot Federman,Doug Stryke,Benjamin Briggs,Charles Langelier,Amy C. Berger,Vanja C. Douglas,S. Andrew Josephson,Felicia C. Chow,Brent D. Fulton,Joseph L. DeRisi,Jeffrey M. Gelfand,Samia N. Naccache,Jeffrey M. Bender,Jennifer Dien Bard,Jamie A. Murkey,Magrit Carlson,Paul M. Vespa,Tara Vijayan,Paul R Allyn,Shelley Campeau,Romney M. Humphries,Jeffrey D. Klausner,Czarina Ganzon,Fatemeh Memar,Nicolle Anne Ocampo,Lara Zimmermann,Stuart H. Cohen,Christopher R. Polage,Roberta L. DeBiasi,Barbara Haller,Ronald H. Dallas,Gabriela Maron,Randall T. Hayden,Kevin Messacar,Samuel R. Dominguez,Steve Miller,Charles Y. Chiu +42 more
TL;DR: Routine microbiologic testing is often insufficient to detect all neuroinvasive pathogens, so metagenomic NGS of CSF obtained from patients with meningitis or encephalitis improved diagnosis of neurologic infections and provided actionable information in some cases.