H
H. P. McDowell
Researcher at Eaton Corporation
Publications - 1
Citations - 1146
H. P. McDowell is an academic researcher from Eaton Corporation. The author has contributed to research in topics: Phosphorylation & Transcription Factor RelA. The author has an hindex of 1, co-authored 1 publications receiving 1073 citations.
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Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression
David E. Nelson,Adaoha E. C. Ihekwaba,M Elliott,James R. Johnson,C. A. Gibney,B. E. Foreman,Glyn Nelson,Violaine Sée,Caroline A. Horton,David G. Spiller,Steven W. Edwards,H. P. McDowell,John Unitt,Elaine Sullivan,Rachel L. Grimley,Neil Benson,David S. Broomhead,Douglas B. Kell,Michael R. H. White +18 more
TL;DR: Single-cell time-lapse imaging and computational modeling of NF-κB (RelA) localization showed asynchronous oscillations following cell stimulation that decreased in frequency with increased IκBα transcription.