H
Habib Zouali
Researcher at Council on Education for Public Health
Publications - 47
Citations - 11692
Habib Zouali is an academic researcher from Council on Education for Public Health. The author has contributed to research in topics: Glucokinase & Inflammatory bowel disease. The author has an hindex of 27, co-authored 45 publications receiving 11310 citations. Previous affiliations of Habib Zouali include French Institute of Health and Medical Research.
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Journal ArticleDOI
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Jean-Pierre Hugot,Mathias Chamaillard,Mathias Chamaillard,Habib Zouali,Suzanne Lesage,Jean-Pierre Cézard,Jacques Belaiche,Sven Almer,Curt Tysk,Colm O'Morain,Miquel A. Gassull,Vibeke Binder,Yigael Finkel,Antoine Cortot,Robert Modigliani,Pierre Laurent-Puig,C. Gower-Rousseau,J. Macry,Jean-Frederic Colombel,Mourad Sahbatou,Gilles Thomas,Gilles Thomas +21 more
TL;DR: It is suggested that the NOD2 gene product confers susceptibility to Crohn's disease by altering the recognition of these components and/or by over-activating NF-kB in monocytes, thus documenting a molecular model for the pathogenic mechanism of Crohn’s disease that can now be further investigated.
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CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease.
Suzanne Lesage,Habib Zouali,Jean-Pierre Cézard,Jean-Frederic Colombel,Jacques Belaiche,Sven Almer,Curt Tysk,Colm O'Morain,Miquel A. Gassull,Vibeke Binder,Yigael Finkel,Robert Modigliani,Corinne Gower-Rousseau,J. Macry,Françoise Merlin,Mathias Chamaillard,Anne-Sophie Jannot,Gilles Thomas,Jean-Pierre Hugot +18 more
TL;DR: The mutational analyses of CARD15 in 453 patients with CD, including 166 sporadic and 287 familial cases, 159 patients with ulcerative colitis (UC), and 103 healthy control subjects provide tools for a DNA-based test of susceptibility and for genetic counseling in inflammatory bowel disease.
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CARD15 mutations in Blau syndrome.
Corinne Miceli-Richard,Suzanne Lesage,Michel Rybojad,Anne-Marie Prieur,Sylvie Manouvrier-Hanu,Renate Häfner,Mathias Chamaillard,Mathias Chamaillard,Habib Zouali,Gilles Thomas,Gilles Thomas,Jean-Pierre Hugot +11 more
TL;DR: Findings indicate that, in addition to Crohn disease, CARD15 is involved in the susceptibility to a second granulomatous disorder.
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Familial Hyperglycemia Due to Mutations in Glucokinase -- Definition of a Subtype of Diabetes Mellitus
Philippe Froguel,Habib Zouali,Nathalie Vionnet,Gilberto Velho,M Vaxillaire,F. Sun,Suzanne Lesage,Markus Stoffel,Jun Takeda,Philippe Passa +9 more
TL;DR: Mutations in glucokinase are the primary cause of hyperglycemia in a substantial fraction of French patients with maturity-onset diabetes of the young and result in a relatively mild form of NIDDM that can be diagnosed in childhood.
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Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus
Nathalie Vionnet,Markus Stoffel,J. Takeda,K. Yasuda,Graeme I. Bell,Habib Zouali,Suzanne Lesage,Gilberto Velho,F. Iris,Ph. Passa,Philippe Froguel,David M. Cohen +11 more
TL;DR: The identification of a nonsense mutation in the gene encoding glucokinase and its linkage with early-onset diabetes in one family is reported, the first evidence implicating a mutation in a gene involved in glucose metabolism in the pathogenesis of NIDDM.