H
Heather Spencer Feigelson
Researcher at Kaiser Permanente
Publications - 169
Citations - 18758
Heather Spencer Feigelson is an academic researcher from Kaiser Permanente. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 53, co-authored 144 publications receiving 17263 citations. Previous affiliations of Heather Spencer Feigelson include American Cancer Society.
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Journal ArticleDOI
Mortality over a Period of 10 Years in Patients with Peripheral Arterial Disease
Michael H. Criqui,Robert Langer,Arnost Fronek,Heather Spencer Feigelson,Melville R. Klauber,Theresa J. McCann,Deirdre Browner +6 more
TL;DR: A 15-fold increase in rates of mortality due to cardiovascular disease and coronary heart disease among subjects with large-vessel peripheral arterial disease that was both severe and symptomatic was revealed.
Journal ArticleDOI
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
David J. Hunter,David J. Hunter,Peter Kraft,Kevin B. Jacobs,David G. Cox,Meredith Yeager,Meredith Yeager,Susan E. Hankinson,Sholom Wacholder,Zhaoming Wang,Zhaoming Wang,Robert W Welch,Robert W Welch,Amy Hutchinson,Amy Hutchinson,Junwen Wang,Junwen Wang,Kai Yu,Nilanjan Chatterjee,Nick Orr,Walter C. Willett,Graham A. Colditz,Regina G. Ziegler,Christine D. Berg,Saundra S. Buys,Catherine A. McCarty,Heather Spencer Feigelson,Eugenia E. Calle,Michael J. Thun,Richard B. Hayes,Margaret A. Tucker,Daniela S. Gerhard,Joseph F. Fraumeni,Robert N. Hoover,Gilles Thomas,Stephen J. Chanock +35 more
TL;DR: Four SNPs in intron 2 of FGFR2 (which encodes a receptor tyrosine kinase and is amplified or overexpressed in some breast cancers) that were highly associated with breast cancer were identified and confirmed in 1,776 affected individuals and 2,072 controls from three additional studies.
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Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
Meredith Yeager,Nick Orr,Richard B. Hayes,Kevin B. Jacobs,Peter Kraft,Sholom Wacholder,Mark J Minichiello,Paul Fearnhead,Kai Yu,Nilanjan Chatterjee,Zhaoming Wang,Zhaoming Wang,Robert W Welch,Robert W Welch,Brian Staats,Brian Staats,Eugenia E. Calle,Heather Spencer Feigelson,Michael J. Thun,Carmen Rodriguez,Demetrius Albanes,Jarmo Virtamo,Stephanie J. Weinstein,Fredrick R. Schumacher,Edward Giovannucci,Walter C. Willett,Geraldine Cancel-Tassin,Olivier Cussenot,Antoine Valeri,Gerald L. Andriole,Edward P. Gelmann,Margaret A. Tucker,Daniela S. Gerhard,Joseph F. Fraumeni,Robert N. Hoover,David J. Hunter,David J. Hunter,Stephen J. Chanock,Gilles Thomas +38 more
TL;DR: Observations indicate the presence of at least two independent loci within 8q24 that contribute to prostate cancer in men of European ancestry, and it is estimated that the population attributable risk of the new locus, marked by rs6983267, is higher than the locus marked byrs1447295.
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The Use of Computed Tomography in Pediatrics and the Associated Radiation Exposure and Estimated Cancer Risk
Diana L. Miglioretti,Diana L. Miglioretti,Eric Johnson,Andrew E. Williams,Robert T. Greenlee,Sheila Weinmann,Leif I. Solberg,Heather Spencer Feigelson,Douglas W. Roblin,Michael J. Flynn,Nicholas Vanneman,Rebecca Smith-Bindman +11 more
TL;DR: The increased use of CT in pediatrics, combined with the wide variability in radiation doses, has resulted in many children receiving a high-dose examination, and dose-reduction strategies targeted to the highest quartile of doses could dramatically reduce the number of radiation-induced cancers.
Journal ArticleDOI
Multiple loci identified in a genome-wide association study of prostate cancer
Gilles Thomas,Kevin B. Jacobs,Meredith Yeager,Meredith Yeager,Peter Kraft,Sholom Wacholder,Nick Orr,Kai Yu,Nilanjan Chatterjee,Robert W Welch,Robert W Welch,Amy Hutchinson,Amy Hutchinson,Andrew Crenshaw,Andrew Crenshaw,Geraldine Cancel-Tassin,Brian Staats,Brian Staats,Zhaoming Wang,Zhaoming Wang,Jesus Gonzalez-Bosquet,Jun Fang,Xiang Deng,Xiang Deng,Sonja I. Berndt,Eugenia E. Calle,Heather Spencer Feigelson,Michael J. Thun,Carmen Rodriguez,Demetrius Albanes,Jarmo Virtamo,Stephanie J. Weinstein,Fredrick R. Schumacher,Edward Giovannucci,Walter C. Willett,Olivier Cussenot,Antoine Valeri,Gerald L. Andriole,E. David Crawford,Margaret A. Tucker,Daniela S. Gerhard,Joseph F. Fraumeni,Robert N. Hoover,Richard B. Hayes,David J. Hunter,David J. Hunter,Stephen J. Chanock +46 more
TL;DR: The findings point to multiple loci with moderate effects associated with susceptibility to prostate cancer that, taken together, in the future may predict high risk in select individuals.