https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(06)68880-6.pdf

Mild cognitive impairment

This article attempts to bring together basic and complex information which has been gathered on cellulose structure, principally that of native cellulose, over the last few decades. Even though advances have been made in the field of crystallography, powder crystallography cannot yield a definitive cellulose structure and single crystal diffraction is not possible due to the lack of suitable crystals. Knowledge obtained on the biosynthesis of native cellulose and on the polymorphy of cellulose and its derivatives help our understanding of ultrastructure. Many inconsistencies between early crystallographic studies of native cellulose have been clarified by the discovery that two polymorphs (α and β) of cellulose I exist. Models of the possible ultrastructural arrangements within native cellulose have been put forward over the decades; with advancement in technology, computer simulations of small and large systems are being created to test the viability of these ultrastructural models. It is hoped that this review will aid in the understanding of the complexity and uncertainties that still exist in this subject

Cellulose: the structure slowly unravels

Summary Early diagnosis of Alzheimer's disease (AD) is needed to initiate symptomatic treatment with acetylcholinesterase inhibitors, and will be of even greater significance if drugs aimed at slowing down the degenerative process, such as vaccination regimes and β-secretase and γ-secretase inhibitors, prove to affect AD pathology and to have clinical effect. However, there is no clinical method to determine in which patients mild cognitive impairment (MCI) will progress to AD with dementia, and in which patients MCI is benign. Hence, there is a great clinical need for biomarkers to identify incipient AD in patients with MCI. The CSF biomarkers total tau protein, phosphorylated tau protein, and the 42 amino-acid residue form of amyloid-β may, if put in the right clinical context, prove to have high enough diagnostic accuracy to meet this challenge.

https://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(03)00530-1.pdf

CSF markers for incipient Alzheimer's disease

Chromatographic separation, identification, and analysis of phosphatides

Activation by Adenosine Triphosphate in the Phosphorylation Kinetics of Sodium and Potassium Ion Transport Adenosine Triphosphatase

A software defined radio with the analog stage using the direct conversion principle and the digital stage using a DSP demodulator has been developed. The developed receiver realizes a multi-band characteristic of the 1.5 GHz and 1.9 GHz bands and a broadband characteristic up to 10 MHz together with a demodulation function of /spl pi//4-QPSK and GMSK, and the overall receiver performance was confirmed.

A software defined radio receiver using the direct conversion principle: implementation and evaluation

System-Level Compensation Approach to Overcome Signal Saturation, DC Offset, and 2nd-Order Nonlinear Distortion in Linear Direct Conversion Receiver

Ribonuclease F1, the guanine-specific ribonuclease of Fusarium moniliforme, was purified to homogeneity by a combination of ethanol fractionation, affinity chromatography and DEAE-cellulose column chromatography. The adsorbent for the affinity chromatography was synthesized by the coupling of periodate-oxidized guanosine 5'-monophosphate to aminohexyl agarose followed by sodium borohydride reduction. Ribonuclease F2, the minor component, was also purified to near homogeneity by the same procedure. Ribonucleases F1 and F2 had the same molecular weight (about 11,000) as determined by gel filtration and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. They also showed the same amino acid composition and differed only in the isoelectric point: 4.10 for F1 and 3.96 for F2.

Purification by affinity chromatography and physicochemical properties of the guanine-specific ribonuclease of Fusarium moniliforme.

PROBLEM TO BE SOLVED: To provide a small high frequency filter which can make its characteristics variable using an outside control measure, making the frequency stability high, making the change small over time, and has a wide frequency change range. SOLUTION: The filter has a thin film piezoelectric resonator 11 connected in series to input and output terminals 14, 15, a parallel thin film piezoelectric resonator 12 connected in parallel to the input and output terminals 14, 15, and a variable voltage circuit 19 which can change at least one of the impressed voltage for the series thin film piezoelectric resonator 11 or the parallel thin film piezoelectric resonator 12. The pass property is changed by changing at least one of the resonation property of the series thin film piezoelectric resonator or the parallel thin film piezoelectric resonator by changing the voltage V1 or V2 in the variable voltage circuit. COPYRIGHT: (C)2004,JPO

Hiroshi Yoshida

Papers

A software defined radio receiver using the direct conversion principle: implementation and evaluation

System-Level Compensation Approach to Overcome Signal Saturation, DC Offset, and 2nd-Order Nonlinear Distortion in Linear Direct Conversion Receiver

Purification by affinity chromatography and physicochemical properties of the guanine-specific ribonuclease of Fusarium moniliforme.

High frequency filter and high frequency filter device

Studies on the venom components of the long-glanded coral snake, Maticora bivirgata.